Diagnostic and therapeutic approach to a case of odontogenic keratocyst
Keywords:
CIRUGÍA BUCAL; DIAGNÓSTICO BUCAL; QUISTES ODONTOGÉNICOS; REGENERACIÓN ÓSEA., SURGERY, ORAL; DIAGNOSIS, ORAL; ODONTOGENIC CYSTS; BONE REGENERATION., CIRURGIA BUCAL; DIAGNÓSTICO BUCAL; CISTOS ODONTOGÊNICOS; REGENERAÇÃO ÓSSEA.Abstract
Introduction: the odontogenic keratocyst is a benign epithelial lesion with aggressive behavior and high recurrence, whose early detection is essential to preserve maxillofacial function.
Objective: to present the diagnostic and therapeutic approach of a clinical case of odontogenic keratocyst in a young patient.
Case presentation: a 23-year-old male patient from riobamba was described, with an incidental radiographic finding of a unilocular radiolucent image associated with the impacted lower left third molar. Clinical examination revealed no alterations. Extraction of the molar was performed, followed by enucleation of the lesion, curettage, and application of carnoy’s solution, complemented with excisional biopsy. Histopathological analysis confirmed a parakeratinized odontogenic keratocyst, characterized by stratified squamous epithelium with prominent nuclei and satellite cysts. Clinical and radiographic follow-up at three months showed adequate bone regeneration and absence of recurrence. Management included conservative techniques combined with adjuvants to reduce the risk of relapse, prioritizing the preservation of anatomical structures.
Conclusions: this case highlights the importance of early diagnosis and personalized treatment. The combination of marsupialization, enucleation, and Carnoy’s solution represents an effective alternative to decrease recurrence, ensuring functionality and aesthetics in young patients.
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1. Velazque Rojas L, Alonso Claudio C, Valenzuela Huamán CJ, Velazque Rojas G, Velazque Rojas L, Alonso Claudio C, et al. Diagnóstico y tratamiento conservador del queratoquiste odontogénico. Odontoestomatología [Internet]. junio de 2022 [citado 13/07/2024]; 24(39): e407. Disponible en: http://www.scielo.edu.uy/scielo.php?script=sci_abstract&pid=S1688-93392022000101407&lng=es&nrm=iso&tlng=es
2. Sosa S RD. Queratoquiste Odontogénico: Revisión de la literatura. Reporte de dos Casos Clínicos. Acta Odontológica Venez [Internet]. diciembre de 2002 [citado 13/07/2024]; 40(3): 276-81. Disponible en: http://ve.scielo.org/scielo.php?script=sci_abstract&pid=S0001-63652002000300005&lng=es&nrm=iso&tlng=es
3. Ramírez LL de L, Hernández NM, Fuentes PMB. ¿Queratoquiste odontogénico o quiste primordial? Actualización diagnóstica y terapéutica. Rev Científica Estud 2 Diciembre [Internet]. 30 de septiembre de 2021 [citado 13/07/2024]; 4(4): e167. Disponible en: https://revdosdic.sld.cu/index.php/revdosdic/article/view/167
4. Cadena AJL, Muñiz LG, Tapia PDC, Flores TA, Orozco JME. Queratoquiste odontogénico. Revisión de 20 años en la Unidad Médica de Alta Especialidad, Hospital de Especialidades CMN «La Raza» IMSS 1980-2000. Rev Mex Cir Bucal Maxilofac [Internet]. 2010 [citado 13/07/2024]; 6(1):4-13. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=24205
5. Bava EJ, Ortolani A, Pantyrer M. Queratoquiste odontogénico múltiple en un paciente pediátrico. Rev Asoc Odontol Argent [Internet]. 2018 [citado 13/07/2024]; 106: 35-40. Disponible en: https://docs.bvsalud.org/biblioref/2018/06/904864/queratoquiste-odontogenico.pdf
6. de Frutos GA, Cuéllar CN, Caicoya SO, López AL, Kulyapina A, Sevilla AG, et al. Manejo terapéutico del queratoquiste: Revisión y presentación de un caso clínico. Revista Mexicana de Cirugía Bucal y Maxilofacial [Internet]. 2014 [citado 13/07/2024]; 10(3): 101-107. Disponible en: https://www.medigraphic.com/pdfs/cirugiabucal/cb-2014/cb143d.pdf
7. Quintana Díaz JC, Miranda Tarragó J, Al-Gobhari F. Queratoquiste odontogénico. Rev Cuba Estomatol [Internet]. septiembre de 2009 [citado 13/07/2024]; 46(3): 70-7. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0034-75072009000300008&lng=es&nrm=iso&tlng=es
8. Andrade Góngora L. Queratoquiste Odontogenico. Reporte de un caso y revision de la Literatura [Internet]. Universidad Nacional Autónoma de México; 2019 [citado 13/07/2024]. Disponible en: https://www.odonto.unam.mx/sites/default/files/inline-files/Andrade%20G%C3%B3ngora%20Leopoldo%20%202019.pdf
9. Khan AA, Qahtani SA, Dawasaz AA, Saquib SA, Asif SM, Ishfaq M, et al. Management of an extensive odontogenic keratocyst. Medicine (Baltimore) [Internet]. 20 de diciembre de 2019 [citado 13/07/2024]; 98(51): e17987. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940056/
10. Beltrán JV, Castillo MO, Basulto RDM. Queratoquiste odontogénico: a propósito de un caso. Progaleno [Internet]. 7 de marzo de 2019 [citado 13/07/2024]; 2(1):33-9. Disponible en: https://revprogaleno.sld.cu/index.php/progaleno/article/view/104
11. Sánchez JS, Maldonado JA, Haro KB, Zuñiga PJ. Queratoquiste odontogénico: características diagnósticas y tratamiento quirúrgico conservador. Int J Med Surg Sci [Internet]. 1 de octubre de 2021 [citado 13/07/2024]; 8(4):1-12. Disponible en: file:///C:/Users/User/Downloads/Dialnet-QueratoquisteOdontogenico-8856767.pdf
12. Tabrizi R, Hosseini Kordkheili MR, Jafarian M, Aghdashi F. Decompression or Marsupialization; Which Conservative Treatment is Associated with Low Recurrence Rate in Keratocystic Odontogenic Tumors? A Systematic Review. J Dent [Internet]. septiembre de 2019 [citado 13/07/2024]; 20(3): 145-51. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732175/
13. Polak K, Jędrusik-Pawłowska M, Drozdzowska B. Odontogenic keratocyst of the mandible: A case report and literature review. Dent Med Probl [Internet]. 28 de octubre de 2019 [citado 13/07/2024]; 56(4): 433-6. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31689015/
14. Titinchi F. Protocol for management of odontogenic keratocysts considering recurrence according to treatment methods. J Korean Assoc Oral Maxillofac Surg [Internet]. 2020 Oct 31 [citado 13/07/2024]; 46(5): 358-360. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33122462/
15. Ochoa Moreira JA, Reinoso Quezada SJ, Molina-Barahona M. Técnicas para el tratamiento del queratoquiste, revisión de la literatura y presentación de un caso. Rev Cient Odontol (Lima) [Internet]. [citado 13/07/2024];11(2): e159. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10809971/
16. Gudiño J, Seijas A, Ghanem AA, Cedeño MJA, Martínez TJL, Castillo T, et al. Queratoquiste Odontogénico: presentación de un caso clínico. Acta Odontológica Venez [Internet]. enero de 2003 [citado 13/07/2024]; 41(1): 39-42. Disponible en: http://ve.scielo.org/scielo.php?script=sci_abstract&pid=S0001-63652003000100007&lng=es&nrm=iso&tlng=es
17. Erbaşar GNH, Peker E, Barış E. Keratocystic odontogenic tumor simulating lateral periodontal cyst and nasopalatine duct cyst: report of cases and literature review. Int J Clin Exp Med [Internet]. 2016 [citado 13/07/2024]; 9(9): 18583-18592. Disponible en: https://e-century.us/files/ijcem/9/9/ijcem0032476.pdf
18. Castillo Canseco H, Piedra Burneo J, Salgado Chavarría F, Prada Vidarte O. Queratoquiste recidivante: Experiencia clínica aplicando diversos métodos de tratamiento. Reporte de dos casos. Odontol Sanmarquina [Internet]. 30 de diciembre de 2023 [citado 13/07/2024]; 26(4): e24819. Disponible en: https://revistasinvestigacion.unmsm.edu.pe/index.php/odont/article/view/24819
19. Quezada Márquez MM, Delgado-Azañero W, Calderón Ubaqui V. Características radiográficas de los queratoquistes odontogénicos paraqueratinizados del maxilar inferior. Rev Estomatológica Hered [Internet]. 25 de septiembre de 2014 [citado 13/07/2024]; 15(2): 112-118. Disponible en: https://drevistas.cayetano.pe/index.php/REH/article/view/1940
20. Sánchez Burgos R, Castillo Pardo de Vera JLD, Morán Soto MJ, Pingarrón Martín L, Burgueño García M. Queratoquiste odontogénico mandibular: Presentación como trismus de larga evolución. Rev Esp Cir Oral Maxilofac [Internet]. agosto de 2008 [citado 13/07/2024]; 30(4): 291-4. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-05582008000400010
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