Risk factors for Alzheimer’s disease in the pre-geriatric population of a medical office
Keywords:
DEMENTIA, ALZHEIMER DISEASE, RISK FACTOR.Abstract
Introduction: numerous studies have referred to the prediction of Alzheimer's disease based on risk factors, but there are insufficient studies that identify or characterize these factors in the pregeriatric population.
Objective: to characterize the risk factors for Alzheimer's disease in a pre-geriatric population in a medical office.
Methods: an observational, descriptive, cross-sectional study was carried out from January to June 2023. From a study universe of 165 patients aged 45 to 59 years, a sample of 140 was formed, by non-probabilistic sampling and at the discretion of the authors. A database was created and processed using descriptive statistics, through mathematical calculations for distribution of absolute and relative frequencies.
Results: the age group of 55-59 years predominated with 42,15 % and the female sex with 57,14 %, where there was a greater frequency and concurrence of risk factors. Sedentary lifestyle stood out at 56,43 %, poor economic situation at 42,14 % and social isolation at 39,29 %. The upper middle level reached 47,14 %. Patients at risk between 50 and 59 years old represented 75 %. More than 50 % have three or more risks.
Conclusions: several of the main risk factors for Alzheimer's disease occur with high frequency and concurrence in patients under 60 years of age, who can still be operated on, taking advantage of their high educational level.
Downloads
References
1. WHO. Dementia [Internet]. Geneva: World Health Organization; 2023 [citado 15/09/2023]. Disponible en: http://www.who.int/es/news-room/fact-sheets/detail/dementia
2. Sánchez M, Veja JC. La enfermedad de Alzheimer desde un análisis métrico de la producción científica de Cuba. Rev Cuba Inf Cienc Salud [Internet]. 2016 [citado 15/09/2023]; 27(1): 35-55. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2307-21132016000100004
3. Pérez M, Álvarez T, Martínez EJ, Valdivia S, Borroto I, Pedraza H. El síndrome del cuidador en cuidadores principales de ancianos con demencia Alzhéimer. Gac Méd Espirit [Internet]. 2017 [citado 15/09/2023]; 19(1): 38-50. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1608-89212017000100007
4. Seima MD, Lenardt MH, Caldas CP. Relação no cuidado entre o cuidador familiar e o idoso com Alzheimer. Rev Bras Enferm [Internet]. 2014 [citado 15/09/2023]; 67(2): 233-40. Disponible en: https://www.scielo.br/j/reben/a/9yw85WQcHq5RT6RpVmssvxg/abstract/?lang=pt
5. American Psychiatric Association. DSM-5. Manual diagnóstico y estadístico de los trastornos mentales [Internet]. 5ed. Buenos Aires: Editorial Médica Panamericana; 2016 [citado: 15/09/2023]. Disponible en: https://www.federaciocatalanatdah.org/wp-content/uploads/2018/12/dsm5-manualdiagnsticoyestadisticodelostrastornosmentales-161006005112.pdf
6. Llibre Rodríguez JJ, Gutiérrez Herrera R, Guerra Hernández MA. Enfermedad de Alzheimer: actualización en su prevención, diagnóstico y tratamiento. Rev haban cienc méd [Internet]. 2022 [15/09/2023]; 21(3): e4702. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/4702
7. Calderón Campos MK, Parodi FJ, Runzer Colmenares MF. Comorbilidades neurológicas y su relación con la velocidad de la marcha en adultos mayores del Centro Médico Naval “Cirujano Mayor Santiago Távara” 2010-2015. Rev Neuropsiquiatr [Internet]. 2019 [citado 15/09/2023]; 82(2): 110-116. Disponible en: https://doi.org/10.20453/rnp.v82i2.3537
8. Lau H, Arimi Fitri LM, Shahar S, Badrasawi M, Clark CB. Factors associated with motoric cognitive risk syndrome among low-income older adults in Malaysia. BMC Public Health [Internet]. 2019 [citado 15/09/2023]; 19(4): 462. Disponible en: https://doi.org/10.1186/s12889-019-6869-z
9. Ocaña Montoya MC, Montoya Pedrón A, Bolaño Díaz AG. Perfil clínico neuropsicológico del deterioro cognitivo subtipo posible Alzheimer. MEDISAN [Internet]. 2019 [citado 15/09/2023]; 23(5): 875-891. Disponible en: http://www.medisan.sld.cu/index.php/san/article/view/2719
10. Hernández Ulloa E, Llibre Rodríguez JJ, Bosh Bayard R, Zayas Llerena T. Prevalencia y factores de riesgo del síndrome demencial en personas mayores. Rev Cubana Med Gen Integr [Internet]. 2021 [citado 15/09/2023]; 37(3): e1409. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21252021000300005&lng=es
11. Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. The Lancet [Internet]. 2020 [citado 15/09/2023]; 396(10248): 413-446. Disponible en: https://doi.org/10.1016/s0140-6736(20)30367-6
12. Mejia Arango S, Garcia Cifuentes E, Samper Ternent R, Borda MG, Cano Gutierrez CA. Socioeconomic Disparities and Gender Inequalities in Dementia: a Community-Dwelling Population Study from a Middle-Income Country. Journal of Crosscultural Gerontology [Internet]. 2021 [citado 15/09/2023]; 36(1): 105-118. Disponible en: https://doi.org/10.1007/s10823-020-09418-4
13. Borda MG, Santacruz JM, Aarsland D, Camargo Casas S, Cano Gutiérrez CA, Suárez Monsalve S, et al. Association of depressive symptoms and subjective memory complaints with the incidence of cognitive impairment in older adults with high blood pressure. European Geriatric Medicine [Internet]. 2019 [citado 15/09/2023]; 10(3): 413-420. Disponible en: https://doi.org/10.1007/s41999-019-00185-1
14. Fratiglioni L, Marseglia A, Dekhtyar S. Ageing without dementia: can stimulating psychosocial and lifestyle experiences make a difference? The Lancet. Neurology [Internet]. 2020 [citado: 15/09/2023]; 19(6): 533-543. Disponible en: https://doi.org/10.1016/S1474-4422(20)30039-9
15. Stern Y, Arenaza Urquijo EM, Bartrés Faz D, Belleville S, Cantilon M, Chetelat G, et al. Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance. Alzheimer’s & Dementia: the Journal of the Alzheimer’s Association [Internet]. 2020 [citado: 15/09/2023]; 16(9):1305-1311. Disponible en: https://doi.org/10.1016/j.jalz.2018.07.219
16. Nelson ME, Jester DJ, Petkus AJ, Andel R. Cognitive Reserve, Alzheimer's Neuropathology, and Risk of Dementia: A Systematic Review and Meta-Analysis. Neuropsychol Rev [Internet]. 2021 [citado: 15/09/2023]; 31(2):233-250. Disponible en: https://doi.org/10.1007/s11065-021-09478-4
17. Darwish H, Farran N, Assaad S, Chaaya M. Cognitive Reserve Factors in a Developing Country: Education and Occupational Attainment Lower the Risk of Dementia in a Sample of Lebanese Older Adults. Frontiers in Aging Neuroscience [Internet]. 2018 [citado: 15/09/2023]; 10:277. Disponible en: https://doi.org/10.3389/fnagi.2018.00277
Downloads
Published
How to Cite
Issue
Section
License
Authors who have publications with this journal agree to the following terms: Authors will retain their copyrights and grant the journal the right of first publication of their work, which will be publication of their work, which will be simultaneously subject to the Creative Commons Attribution License (CC-BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.
Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g.: deposit it in an institutional telematic archive or publish it in a volume). Likewise, and according to the recommendations of the Medical Sciences Editorial (ECIMED), authors must declare in each article their contribution according to the CRediT taxonomy (contributor roles). This taxonomy includes 14 roles, which can be used to represent the tasks typically performed by contributors in scientific academic production. It should be consulted in monograph) whenever initial publication in this journal is indicated. Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which may produce interesting exchanges and increase citations of the published work. (See The effect of open access). https://casrai.org/credit/