Neuroblastoma of the adrenal gland in twin pregnancy

Authors

  • Luis Raúl Martínez González Centro Provincial de Genética Médica Pinar del Río.
  • Dianelys Pérez Rodríguez Centro Provincial de Genética Médica Pinar del Río.
  • Caridad Pérez Martínez Centro Provincial de Genética Médica Pinar del Río.

Keywords:

Adrenal glands, Neuroblastoma, Abdominal neoplasms.

Abstract

Introduction: the anomalies of adrenal glands are rarely detected during prenatal life, they can be observed on the second half of pregnancy, cysts and hemorrhages are the most frequent anomalies found; solid tumors are rare. Though, ultrasonographic advances make possible the intrauterine detection, its prenatal diagnosis is not frequent. This kind of tumor presents a high rate of morbidity and mortality due to its metastatic risk.
A case report: a fetal ultrasonography to a twin pregnancy at 23 weeks was performed and informed as a normal test, but a solid hyper-echogenic mass was detected above the left kidney of one of the fetus.
Conclusions: a neuroblastoma of the adrenal gland was the main diagnosis. Pregnancy was interrupted having the previous consent of the couple, pathological studies confirmed the diagnosis.

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Author Biographies

Luis Raúl Martínez González, Centro Provincial de Genética Médica Pinar del Río.

Doctor en Medicina. Especialista de segundo Grado en Ginecología y Obstetricia. Máster en Ciencias en  Atención Integral a la Mujer. Profesor Instructor.

Dianelys Pérez Rodríguez, Centro Provincial de Genética Médica Pinar del Río.

Doctor en Medicina. Especialista de primer Grado en Ginecología y Obstetricia. Máster en Atención Integral a la Mujer. Profesora Auxiliar.

Caridad Pérez Martínez, Centro Provincial de Genética Médica Pinar del Río.

Doctor en Medicina. Especialista de primer grado en Ginecología y Obstetricia.

References

1. Oliva Rodríguez. JA. Ultrasonografía diagnóstica fetal, obstétrica y ginecológica. Habana: Editorial Ciencias Médicas; 2010.

2. Kanagarajah P, Ayyathurai R, Manoharan M, Narayanan G, Kava BR. Current concepts in the management of adrenal incidentalotas. Urol Ann [Internet]. 2012 [citado 18 Mar 2013]; 4(3):[aprox. 7 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519103/

3. Woodruff S, Yeunga M, Grodskia S, Johnsona W, Serpella J. Adrenal Injuries and Incidentalomas in Trauma Patients at an Urban Trauma Centre. J Curr Surg [Internet]. 2012 [citado 18 Mar 2013]; 2(4-5):[aprox. 7 p.]. Disponible en: http://www.jcs.elmerpress.com/index.php/jcs/article/view/108/71

4. Carrillo D, Ibarra X, Cuevas M, de Barbieri F, Oyanedel R , Zavala A, et al. Causa infrecuente de hipertensión arterial en lactantes: neuroblastoma congénito quístico suprarrenal. Caso clínico. Rev Chil Pediatr [Internet]. 2012 [citado 24 Feb 2013]; 83(3):[aprox. 7 p.]. Disponible en: http://www.scielo.cl/pdf/rcp/v83n3/art08.pdf

5. Mullassery D, Dominici C, Jesudason EC, McDowell HP, Losty PD. Neuroblastoma: contemporary management. Arch Dis Child Educ Pract Ed [Internet]. 2009 [citado 24 Feb 2013]; 94(6):[aprox. 9 p.]. Disponible en: http://ep.bmj.com/content/94/6/177.full.pdf+html

6. Leary RJ, Jones S, Wu J, Reynolds CP, Liu X, Blackford A, et al. Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma. Nature Genetics [Internet]. 2013 [citado 24 Feb 2013]; 45(1):[aprox. 6 p.]. Disponible en: http://www.nature.com/ng/journal/v45/n1/full/ng.2493.html

7. Sherer DM, Dalloul M, Wagreich A, Sokolosky M, Duan H, Zinn H, et al. Prenatal Sonographic Findings of Congenital Adrenal Cortical Adenoma. JUM [Internet]. 2008 [citado 24 Feb 2013]; 27(7):[aprox. 3 p.]. Disponible en: http://www.jultrasoundmed.org/content/27/7/1091.full.pdf+html

8. Castagnaro Rosini MN, Castagnaro MC. Masas retroperitoneales en el periodo perinatal. Rev argent radiol [Internet]. 2011 [citado 24 Feb 2013]; 75(1):[aprox. 9 p.]. Disponible en: http://www.scielo.org.ar/pdf/rar/v75n1/v75n1a08.pdf

9. Crespo Esteras R, Alvir Álvaro A, Campillos Maza JM, Tobajas Homs JJ. Diagnóstico prenatal de Neuroblastoma retroperitoneal. Reporte de un caso. Ginecol Obstet Mex [Internet]. 2010 [citado 24 Feb 2013]; 78(4):[aprox. 5 p.]. Disponible en: http://www.medigraphic.com/pdfs/ginobsmex/gom-2010/gom104g.pdf

10. Blackman SC, Evenson AR, Voss SD. Prenatal diagnosis and subsequent treatment of an intermediate-risk paraspinal neuroblastoma: case report and review of the literature. Fetal Diagn Ther. 2008; 24(2):119-125.

Published

2013-06-21

How to Cite

1.
Martínez González LR, Pérez Rodríguez D, Pérez Martínez C. Neuroblastoma of the adrenal gland in twin pregnancy. Rev Ciencias Médicas [Internet]. 2013 Jun. 21 [cited 2025 Oct. 13];17(3):179-85. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/1065

Issue

Section

CASE REPORTS