Radiosurgery in cervicaluterine cancer prevention program in Pinar del Río

Authors

  • José Guillermo Sanabria Negrín Universidad de Ciencias Médicas de Pinar del Río
  • Víctor Enrique Salgueiro Medina Consulta Provincial de Patología de Cuello, Hospital General Docente "Abel Santamaría Cuadrado"
  • Raydel Marrero Fernandez Departamento de Morfofisiología. Universidad de Ciencias Médicas de Pinar del Río.
  • María Cristina Cardonell Lorenzo Hospital General Docente "Abel Santamaría Cuadrado"

Keywords:

Radiosurgery, Cervix uteri, Neoplasms, Uterine cervical neoplasms.

Abstract

Introduction: radiosurgery as a diagnosis and therapeutical means is used in Pinar del Río from November 2003, and the assessment of its effectiveness should be parmanent.
Objective: to evaluate the impact of the use of the radiosurgery cone on Pinar del Río from 2004-12.
Material and methods: An observation, descriptive and retrospective study in the Province Department of Cervix Pathology at Abel Santamaria Cuadrado University General Hospital (patients from the diagnosis program or not). Methods of descriptive statistics were used, and the Pearson correlation coefficient, ANOVA and Student´s T test.
Results: 15,836 women attended, out of which 6,695 (42.3%) received readiosurgey, 774 by year average, from all of the municipalities and none under anaesthsia. 49.5% of the program (38,0±8,7 years, CI 95%: 36,7_39.4 yearsaños), the rest was not in the program (34.3±10.9 years, CI 95%: 33,1-35,5 years). The most frequent diagnosis was cervical intraepithelial neoplasia (CIN1), 44 invasive epidermoid carcinoma in stages Ib or higher and 3 endocervical adenocarcinomas. The positive margins (5.1%) predominated in the patients with carcinoma in situ and the natural history of two cases was invasive carcinoma. 17.8% presented residual disease.
Conclusions: ambulatory radiosurgery is effective when 100% curable lesions are diagnosed. The better state of the surgical piece has been noticeably achieved. Lesser cases with positive margins, and therefore less possibility of residual lesion. There is a positive impact on the Cervicauterine Cancer Early Detection Program.

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Author Biographies

José Guillermo Sanabria Negrín, Universidad de Ciencias Médicas de Pinar del Río

Especialista de II Grado Histología, Profesor Auxiliar. Doctor en Ciencias Biológicas. Dirección Provincial de Ciencia y Tecnología.

Víctor Enrique Salgueiro Medina, Consulta Provincial de Patología de Cuello, Hospital General Docente "Abel Santamaría Cuadrado"

Médico especialista de I y II Grado en Gineco-obstetricia. Máster en Atención a la Mujer.  Profesor Auxiliar de Gineco-Obstetricia.  Jefe de la Consulta Provincial de Patología de Cuello, Pinar del Río, Cuba.

Raydel Marrero Fernandez, Departamento de Morfofisiología. Universidad de Ciencias Médicas de Pinar del Río.

Médico Residente de II Año de HIstología.  Universidad de Ciencias Médicas de Pinar del Río.

María Cristina Cardonell Lorenzo, Hospital General Docente "Abel Santamaría Cuadrado"

Licenciada en Citohistopatología. Jefa técnica del Departamento de Anatomía Patológica del Hospital General Docente "Abel Santamaría Cuadrado"

References

1. Boone JD, Erickson BK, Huh WK. New insight into cervical cancer screening. J Gynecol Oncol 2012 Oct [citado 15-03-13]; 23 (4): 282-287. Disponible en: http://synapse.koreamed.org/search.php?where=aview&id=10.3802/jgo.2012.23.4.282&code=1114JGO&vmode=FULL.

2. Sanabria Negrín JG, Abreu Mérida MB, Salgueiro Medina VE.: Tendencias del cáncer cérvico uterino en Pinar del Río. 1988 a 2004. VII Congreso Virtual Hispanoamericano de Anatomía Patológica y I Congreso de Preparaciones Virtuales por Internet. 2005, 1-31. Disponible en: http://www.conganat.org/7congreso/trabajo.asp?id_trabajo=496

3. Chamot E, Kristensen S, Stringer JSA, Mwanahamuntu MH. Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scalling-up of cervical screening programs? A systematic review. BMC Women´s Health 2010 [citado 26-09-11.]; 10: 11-22. Disponible en: http://www.biomedcentral.com/1472-6874/10/11

4. Nuranna L, Aziz MF, Santoso C, Gatot P, Purbadi S, Budiningsih S , Budiningsih Siregar, Willem Peters AA. Cervical cancer prevention program in Jakarta, Indonesia: See and Treat model in developing country. J. Gynecol Oncol 2012 Jul 23 (3): 147-152. Disponible en: http://synapse.koreamed.org/search.php?where=aview&id=10.3802/jgo.2012.23.3.147&code=1114JGO&vmode=FULL [Acceso 15-07-12]

5. Metz SA, Chief Editor Rivlin ME. Colposcopy. Medscape.com. Updated Jan 12, 2012. Disponible en: http://emedicine.medscape.com/article/265097-overview. [Acceso 15-04-13]

6. Wentzensen N, Schiffman M, Dunn ST, Zuna RE, Walker J, Allen RA, Zhang R, Sherman ME, Wacholder S, Jeronimo J, Gold MA, Wang SS. Grading the severity of cervical neoplasia based on combined histopathology, cytopathology, and HPV genotype distribution among 1700 women referred to colposcopy in Oklahoma. Int J Cancer 2009 Feb 15: 124-(4):964-969. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2796188. [Acceso: 24-03-13]

7. Cuba. MINSAP. Guías de Consenso sobre el cáncer Cervicouterino y lesiones premalignas. Junio de 2011(en prensa).

8. Torriente Hernández B, Valdés O, Lugo Sánchez AM, González González M. Valor de la electrocirugía como tratamiento conservador del carcinoma in situ. Rev Cubana Obstet Ginecol 2002; 28(2). Disponible en: http://bvs.sld.cu/revistas/gin/vol28_2_02/gin10202.htm. [Acceso: 14-05-13]

9. Strander B, Andersson-Ellstrom A, Misom I, et al. Long term risk of invasive cancer after treatment for cervical intraepithelial neoplasia grade 3: population based cohort study. BMJ. 2007; 335 (7629): 1077. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094166/ [Acceso: 15-04-09]

10. Wright TC, Massad LC, Dunton CJ, Spitzer M, Wilkinson EJ, Solomon D. 2006 Consensus guidelines for the management of women with cervical intraepithelial neoplasia or adenocarcinoma in situ. J Lower Genital Tract Dis. 2007; 11 (4): 223 _ 239. Disponible en: http://journals.lww.com/jlgtd/Fulltext/2007/10000/2006_Consensus_Guidelines_for_the_Management_of.1.aspx [Acceso: 31-07-09]

11. Kalliala I, Dyba T, Nieminen P, Hakulinen T, Anttila A. Mortality in a long-term follow-up after trearment of CIN. IJC 2009 jul 7, 126 (1):224-231. Disponible en: http://onlinelibrary.wiley.com/doi/10.1002/ijc.24713/full. [Acceso: 08-06-13]

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Published

2013-12-25

How to Cite

1.
Sanabria Negrín JG, Salgueiro Medina VE, Marrero Fernandez R, Cardonell Lorenzo MC. Radiosurgery in cervicaluterine cancer prevention program in Pinar del Río. Rev Ciencias Médicas [Internet]. 2013 Dec. 25 [cited 2025 Sep. 19];17(6):110-21. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/1314

Issue

Vol. 17 No. 6 (2013)

Section

ORIGINAL ARTICLES

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