Clinical and Epidemiological Aspects of Bacterial Meningitis: "Abel Santamaría "and "León Cuervo Rubio" hospitals, 2002-2006

Authors

  • Ariel I. Corrales Varela Especialista de Primer Grado en Medicina Interna y en Medicina Intensiva y Emergencias. Hospital General Docente "Abel Santamaría Cuadrado". Pinar del Río.
  • Ariel E. Delgado Rodríguez Máster en Urgencias Médicas. Especialista de Primer Grado en Medicina Interna. Especialista de Segundo Grado en Medicina Intensiva y Emergencias. Asistente de Medicina Interna. Hospital General Docente "Abel Santamaría Cuadrado". Pinar del Río.
  • Irene C. Pastrana Román Máster en Urgencias Médicas. Especialista de Segundo Grado en Medicina Interna. Especialista de Segundo Grado en Medicina Intensiva y Emergencias. Profesora Auxiliar y Consultante. Hospital General Docente "Abel Santamaría Cuadrado". Pinar del Río.
  • Carlos Brown Sotolongo Especialista de Primer Grado en Medicina Interna. Verticalizado en Medicina Intensiva y Emergencias. Hospital General Docente "Abel Santamaría cuadrado". Pinar del Río.
  • Damarys Chirino Labrador Máster en Longevidad Satisfactoria. Especialista de Primer Grado en Medicina General Integral. Profesora Auxiliar de MGI. Hospital General Docente "Abel Santamaría Cuadrado". Pinar del Río.

Abstract

A descriptive study was performed from 2002-2006 in 117 patients with a bacterial meningoencephalitis diagnosis being discharged alive or death in "Abel Santamaría" or "Leon Cuervo Rubio" hospitals. The non - parametric statistical X2 testing was used for the statistical validation as well as the hypothesis testing of ratios for independent groups, a fitted value of á=0.05. Most of patients with acute and sub acute bacterial meningoencephalitis were in 15 and 59 year age range decreasing the frequency of the disease with the age advancing , the highest mortality rate was observed at 60 years old or over being considered very significant . The most predisposing factors were: otitis media, acute community pneumonia and sinusitis, some of them partially treated or not. Fever, headache, neck stiffness and consciousness disorders were the most frequent symptoms and signs and the absence of fever, the occurrence of vomits, consciousness disorders, convulsions, and other meningeal signs and petechiae were considered as a bad prognosis. The most frequent complications were cerebral edema, nosocomial acute pneumonia and acute respiratory failure no associated to SIRPA having all of them very significant statistical differences and leading to a probable death. The etiological agents were: Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis, Enterobacter aerogenes, Neisseria meningitides and Haemophilus influenzae. In most of cases given antibiotic therapy before diagnosis the culture was negative.

Downloads

Download data is not yet available.

References

1. Soumaré M,Seydi M,Ndour CT,Fall N, Dieng Y, Sow AI, Diop BM. Epidemiological, clinical, etiological features of neuromeningeal diseases at the Fann Hospital Infectious Diseases Clinic, Dakar (Senegal). Med Mal Infect.[revista en internet] 2005; [citado],35(7-8):383-9. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/15975752

2. Sunakawa K. Analysis by questionnaire survey concerning example such as purulent meningitis and severe infectious diseases. Relation among patient background factors, sequelae, and infecting organism. Jpn J Antibiot. [revista en internet] June 2006; [citado] ,59(3):p.152-64. Disponible en: http://www.ophsource.org/periodicals/ophtha/medline/record/MDLN.16913402

3. Huwendiek S, Tonshoff B. Meningitis in children and adults. Differential diagnostic approach and management. MMW Fortschr Med. 2003; 145(50):38-41.

4. Reinert P. Purulent meningitis: special considerations for developing countries. Med Trop.[revista en internet], 2003; [citado],63(4-5):481-5. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/14763303

5. Lefort A, Fantin B. Purulent meningitis. Rev Prat.[revista en internet]2001; [citado], 51(6):603-7. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/11345860

6. Roca Goderich R, Smith Smith V, Paz Presilla E, Lozada Gómez J, Serret Rodríguez B, Llamos Sierra N, et al. Temas de medicina interna. 4ª. ed. t-2. La Habana: Editorial Ciencias Médicas; 2002.

7. Perrochaau A, De Benoist AC, Six C, Goulet V, Dacludt B, Levy Bruhi D. Epidemiology of bacterial meningitis in France. Ann Med Interne. 2002; 153(5):311-7.

8. Roos KL, Tyler KL. Meningitis bacterianas y otras infecciones supurativas. En: Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, et al. Harrison Principios de Medicina Interna. 15ª. ed. v-2. México: Mc Graw Hill Interamericana; 2002. p.2880-91.

9. Abdul-Wahab B. R. Johnson, Olanrewaju T. Adedoyin, Aishat A. Abdul-Karim, Abdul-Waheed I. Olanrewaju. Childhood pyogenic meningitis: clinical and investigative indicators of etiology and outcome. J Natl Med Assoc.[revista en internet] 2007; [citado],99(8):937-47. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574311/

10. Huang ST,Lee HC,Lee NY, Liu KH, Ko WC. Clinical characteristics of invasive Haemophilus aphrophilus infections. J Microbiol Immunol Infect.[revista en internet] 2005; [citado],38(4):271-6. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16118675

11. Saha SK, Darmstadt GL, Yamanaka N, Billal DS, Nasreen T, Islam M, Hamer DH. Rapid diagnosis of pneumococcal meningitis: implications for treatment and measuring disease burden. Pediatr Infect Dis J. [revista en internet] 2005; [citado] 24(12):1093-8. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16371872

12. Pena Hernández R, Díaz Ramos RD, Solorzano Santos F, Miranda Novales MG. Epidemiología de meningoencefalitis bacteriana en un hospital de pediatría de tercer nivel. Enfermedades infecciosas y microbiología. 2005; 25(1):11-6.

13. Ricciardi L, Meini M, Luchi S, Scasso A, Corbisiero R, Mencarelli M, et al. Bacterial meningitis in adults: a retrospective multicentric study in Tuscany (Italy). Infez Med. 2006; 14(2):77-84.

14. Huwendiek S, Steiner T, Tönshoff B. When should you suspect meningitis?. MMW Fortschr Med. 2007; 149(2): 15-8.

15. Kamei S. Neuroinfection. Nippon Rinsho. 2007; 65(2):215-9.

16. Ishikawa T, Asano Y, Morishima T, Nagashima M, Sobue G, Watanabe K, Yamaguchi H. Epidemiology of bacterial meningitis in children: Aichi Prefecture, Japan, 1984-1993. Pediatr Neurol. [revista en internet]1996; [citado] 14(3):244-50. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/8736410

17. Abe M, Takayarna Y, Yamashita H, Noguchi M, Sagch T. Purulent meningitis with unusual diffusion weighted MRI findings. Eur J Radiol. 2002; 44(1):1-4.

18. Bone RC, Grodzin CJ, Balk RA. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest. 1997; 112:235-43.

19. Álvarez Fumero R, Manresa Gómez L, Castro Pacheco BL, Pérez Orta M, Rojo Casares I, Quintana Jardines I. Manejo hospitalario de la meningoencefalitis bacteriana. Rev Cubana Pediatr. 2003; 75(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312003000400005&lng=es.

20. Elmore JG, Horwitz RI, Quagliarello UJ. Acute meningitis with a negative Gram´s stain: clinical and management outcomes in 171 episodes. Am J Med. 1996; 100(1):78-84.

How to Cite

1.
Corrales Varela AI, Delgado Rodríguez AE, Pastrana Román IC, Brown Sotolongo C, Chirino Labrador D. Clinical and Epidemiological Aspects of Bacterial Meningitis: "Abel Santamaría "and "León Cuervo Rubio" hospitals, 2002-2006. Rev Ciencias Médicas [Internet]. 2012 Oct. 25 [cited 2025 Aug. 29];12(2):51-64. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/433

Issue

Section

ORIGINAL ARTICLES