Pemphigoid gestationis in the third trimester

Authors

Keywords:

PEMPHIGOID GESTATIONIS/diagnosis, PEMPHIGOID, BULLOUS, PREGNANT WOMEN.

Abstract

Introduction: pemphigoid gestationis is a rare blistering disease characterized by an intensely itchy urticarial rash on the trunk and extremities that appears at the end of pregnancy and after delivery. It rapidly evolves into vesiculo ampullary dermatosis of the pemphigoid blistering type, since they have many clinical, histological and immune-pathological similarities.

Objectives: to present the clinical characteristics of a pregnant patient with pemphigoid gestationis.

Case Report:  a pregnant woman with a prenatal history of a normal previous pregnancy; without skin lesions and a current 32-week pregnancy is presented. She was attended in the Dermatology Clinic at Raul Sanchez University Polyclinic where a polymorphic skin condition was evidenced by skin lesions in the form of small multiple, rounded plates of urticarial aspect and erythematous-papular filtered lesions, which were located in the abdomen, lower limbs and very pruritic rash. Clinical elements and histopathological study confirmed the diagnosis of pemphigoid gestationis. She received medical treatment achieving evident clinical progress.

Conclusions: a known clinical case was presented but of scarce incidence, therefore there are problems for its diagnosis and it must be taken into account due to the similarity with other skin dermatoses in pregnant women. It presents a morbidity risk for the newborn, maternal health is preserved in spite of its autoimmune etiology. The adequate diagnosis of this entity will allow a follow up along with an adequate medical treatment by a responsible multidisciplinary team, achieving an adequate quality of life and a better maternal-infant indicator.

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Author Biographies

Julio César Camero Machín, Hospital Provincial Clínico Quirúrgico Docente León Cuervo Rubio

Médico. Especialista de Segundo Grado en Medicina General e Integral y Primer Grado en Dermatología. Máster en Longevidad Satisfactoria. Profesor Asistente. Investigador Agregado.

Erika Fernández Sobrino, Universidad de Ciencias Médicas. Pinar del Río. Cuba

Médico. Especialista de Primer Grado en Medicina General Integral. Instructor

Kiuvys Anuy Echevarría, Hospital Provincial León Cuervo Rubio. Pinar del Río. Cuba

Médico. Especialista de Primer Grado en Dermatología. Máster en Atención Integral a la mujer. Profesor Asistente

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Published

2020-09-23

How to Cite

1.
Camero Machín JC, Fernández Sobrino E, Anuy Echevarría K. Pemphigoid gestationis in the third trimester. Rev Ciencias Médicas [Internet]. 2020 Sep. 23 [cited 2025 Aug. 23];24(5):e4445. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/4445

Issue

Section

CASE REPORTS