Changes in hematological variables and globular sedimentation rate in non-critical patients withCOVID-19

Authors

Keywords:

COVID-19, EPIDEMIOLOGIC FACTORS, PATIENT, HEMATOLOGY, LABORATORY TEST.

Abstract

Introduction: clinical hematology tests and globular sedimentation rate (ESR) have been used as markers of clinical evolution in patients with thenovel coronavirus disease 2019.

Objective: to analyze changes in hematological variables and ESR in patients diagnosed with COVID-19 in non-critical status, admitted to Dr. León Cuervo Rubio Provincial Clinical-surgical Teaching Hospital, between March 16 and May 4, 2020.

Methods: an observational-analytical and longitudinal-prospective study conducted with data from 44 non-critical patients with COVID-19. Samples were examined for: hemoglobin, hematocrit, global leukocyte count, neutrophils, lymphocytes, medium size cells and erythrocyte sedimentation rate; on admission, at 48hours of admission, on the eighth day and on medical discharge. The longitudinal changes of these variables were analyzed by means of the non-parametric Friedman test for k-related samples.

Results: hematological variables: hemoglobin, hematocrit, global leukocyte count, neutrophils and lymphocytes did not have significant changes during the follow up. Only medium size cells decreased significantly in children, when comparing their mean value at discharge in relation to admission (p=0,028) and on the second day of hospitalization (p=0,01). In adult male patients, the ESR significantly decreased at eighth day of admission and at medical discharge, in relation to its value at admission (p=0,008).

Conclusions: the changes observed in the hematological variables assessed, especially in the medium size cellsin children, and erythrocyte sedimentation rate in men with COVID-19 in non-critical status, respond to a favorable clinical evolution.

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Author Biographies

Ivette González Fajardo, Hospital Provincial Docente Clínico Quirúrgico Dr."León Cuervo Rubio"

Médica. Especialista de Segundo Grado en Laboratorio Clínico

Elisa Maritza Linares Guerra, Universidad de Pinar del Río “Hermanos Saiz Montes de Oca”

Doctora en Ciencias

Dianelys Díaz Padilla, Hospital Provincial Docente Clínico Quirúrgico Dr."León Cuervo Rubio"

Especialista de Primer Grado en Laboratorio Clínico

Amaury Núñez Betancourt, Hospital Clínico Quirúrgico Docente Abel Santamaría Cuadrado

ESpecialista de Segundo Grado en Medicina Intensiva y Emergencias

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Published

2020-06-29

How to Cite

1.
González Fajardo I, Linares Guerra EM, Díaz Padilla D, Godoy Lóriga LM, Núñez Betancourt A. Changes in hematological variables and globular sedimentation rate in non-critical patients withCOVID-19. Rev Ciencias Médicas [Internet]. 2020 Jun. 29 [cited 2025 Aug. 21];24(3):e4515. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/4515

Issue

Vol. 24 No. 3 (2020)

Section

ORIGINAL ARTICLES

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