Clinical characterization of patients with renal amyloidosis
Keywords:
AMYLOIDOSIS, AMYLOIDOGENIC PROTEINS, SIGNS AND SYMPTOMS, DIAGNOSIS, RENAL DIALYSIS.Abstract
Introduction: renal amyloidosis is a disease of great clinical importance due to the poor prognosis and short life expectancy of patients who present it.
Objectives: to identify the clinical characteristics of patients with renal amyloidosis seen at the “Dr. Abelardo Buch” Nephrology Institute, between 2010 and 2018.
Methods: observational, descriptive, retrospective cohort study, developed in a population of 26 patients with a diagnosis of renal amyloidosis, attended at the indicated health institution. The documentary review allowed the collection of information that led to the variables analyzed. Descriptive statistical methods were used for the analysis of the information obtained, and medical ethics were respected.
Results: patients in the age group 50-64 years old predominated (57,7 %), being the female sex the most representative (65,4 %). Edema and foamy urine were the main clinical manifestations, being nephrotic syndrome (92,3 %), the main reason for indication of renal biopsy. Renal function replacement therapy was not required in 88,5 % of patients, and 76.9 % of patients survived to six months. Survival was higher for the group of patients who did not require dialytic therapy compared to those who did, although no statistically significant differences were found (p=0,13).
Conclusions: the sample of patients with renal amyloidosis was characterized, evidencing the main clinical characteristics shown by them. A reduction in the survival rate was observed as the disease evolved over time.
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