Effects of Platelet-Rich Fibrin on Various Dental Treatments
Keywords:
FIBRINA RICA EN PLAQUETAS; MATERIALES BIOCOMPATIBLES; ODONTOLOGÍA; REGENERACIÓN TISULAR DIRIGIDA. , PLATELET-RICH FIBRIN; BIOCOMPATIBLE MATERIALS; DENTISTRY; GUIDED TISSUE REGENERATION., FIBRINA RICA EM PLAQUETAS; MATERIAIS BIOCOMPATÍVEIS; ONDONDOLOGIA; REGENERAÇÃO TECIDUAL GUIADA.Abstract
Introduction: platelet-rich fibrin is an autologous biomaterial of growing interest in dentistry due to its regenerative capacity and its potential to optimize wound healing.
Objective: to describe the clinical benefits of platelet-rich fibrin in dental procedures, assessing its effectiveness in soft and hard tissue as well as bone regeneration.
Methods: a systematic review was conducted across different databases. Through the design of an information search algorithm, relevant sources were identified and selected; those that met the established selection criteria were included for analysis of the topic addressed.
Development: the reviewed literature shows that platelet-rich fibrin promotes soft and hard tissue healing, reduces postoperative complications, and improves dental implant integration. Success rates above 75 % are reported in most studies, highlighting its usefulness in oral surgery, periodontics, and implantology. In addition, its three-dimensional structure acts as a biological scaffold that facilitates cell proliferation and angiogenesis. The evidence indicates that it is a versatile, safe, and cost-effective resource, with applications in bone regeneration, closure of sinus cavities, and advanced periodontal treatments.
Conclusions: platelet-rich fibrin is established as an effective therapeutic alternative in dentistry, with the ability to accelerate healing and reduce postoperative risks. Its simplicity of preparation and low cost enhance its clinical applicability; however, further research is recommended to standardize protocols and assess long-term outcomes.
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1. Escalante W, Castro G, Vaz L, Kuga M. Fibrina rica en plaquetas (FRP): Una alternativa terapéutica en odontología. Rev. Estomatol Hered[Internet]. 2016 [Consultado 14/12/2025]; 26(3). Disponible en: https://pesquisa.bvsalud.org/portal/resource/De/biblio-1508519
2. Ballesteros S, Hidalgo P, Armijos F. Fibrina rica en plaquetas y su uso en odontología. Rev Ciencias Médicas[Internet]. 2023 [Consultado 14/12/2025]; 27(Supl1). Disponible en: http://scielo.sld.cu/pdf/rpr/v27s1/1561-3194-rpr-27-s1-e6005.pdf
3. Gutiérrez D, Hinojosa J, Restrepo A, Muñoz A, Velarde N, Bastidas F. Análisis estructural de la fibrina rica en plaquetas y sus aplicaciones en odontología regenerativa. Univ Odontol[Internet]. 2018 [Consultado 14/12/2025]; 37(79). Disponible en: https://revistas.javeriana.edu.co/index.php/revUnivOdontologica/article/view/24589
4. López-Pagán E, Pascual-Serna AC. Fibrina rica en plaquetas en la cicatrización de los tejidos periodontales. Odontol Sanmarquina[Internet]. 2020 [Consultado 14/12/2025]; 23(1): 43-50. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=9373061
5. González M, Jara L. Aplicaciones clínicas de la fibrina rica en plaquetas en odontología: revisión narrativa. Univ El Bosque, Facultad de Odontología. Bogotá[Internet]; 2021 [Consultado 14/12/2025]. Disponible en: https://repositorio.unbosque.edu.co/items/ef84f3ef-c370-4609-8666-3abf09d7de0c
6. Suárez D, Velazco G, Viloria F, Guerrero V, Solorzano E, Montero Y. Fibrina rica en plaquetas inyectable como regenerador del complejo dentinopulpar. Ensayo preclínico. Redoe[Internet]. 2020 [Consultado 14/12/2025]. Disponible en: http://www.redoe.com/ver.php?id=330
7. Guzmán G, Paltas M, Benenaula J, Núñez K, Simbaña D. Cicatrización de tejido óseo y gingival en cirugías de terceros molares inferiores: estudio comparativo entre el uso de fibrina rica en plaquetas versus cicatrización fisiológica. Rev Odontol Mex[Internet]. 2017 [Consultado 14/12/2025]; 21(2): 114-120. Disponible en: https://pesquisa.bvsalud.org/odontologia/resource/espt/biblio-902727
8. Macias G, Santana Y. Uso de fibrina rica en plaquetas como terapéutica osteoinductora y osteoconductora en odontología. En: Aprender a vivir un mundo diferente. Universidad de Zulia. Ed. Astro Data S.A. Maracaibo, Venezuela[Internet]; 2020 [Consultado 14/12/2025]. Disponible en: https://www.researchgate.net/profile/Cesar-Bohorquez-4/publication/352330298_Didactica_del_autoconocimiento/links/60c3d56e92851ca6f8df9f8b/Didactica-del-autoconocimiento.pdf#page=410
9. Atamari V, Sanga C, Huayhua K. Fibrina rica en plaquetas en el cierre clínico de la mucosa alveolar post-exodoncia en pacientes sometidos a cirugía bucal. Evid Odontol Clinic[Internet]. 2017 [Consultado 14/12/2025]; 3(2): 40-45. Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-999878
10. Bettin D, Lopez Z. Regeneración tisular guiada potencializada con fibrina rica en plaquetas en paciente con periodontitis agresiva generalizada: reporte de un caso. CES Odontol[Internet]. 2021 [Consultado 14/12/2025];34(1):125-135. Disponible en: https://pesquisa.bvsalud.org/enfermeria/resource/pt/biblio-1360267
11. Ramírez T, Sossa H. Endodoncia regenerativa: utilización de fibrina rica en plaquetas autóloga en dientes permanentes vitales con patología pulpar. Acta Odontol Colomb[Internet]. 2014 [Consultado 14/12/2025]; 4(1): 91-112 Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=9344161
12. Miquet Vega SA, Báez Ayakà É. Células madre dentales, reparación y regeneración en pulpa
16 de Abril[Internet]. 2019 [Consultado 14/12/2025]; 58(274): 126-130. Disponible en: https://www.medigraphic.com/pdfs/abril/abr-2019/abr19274g.pdf
13. Brizuela C, Saint N. Propuesta de un modelo para lograr la revascularización pulpar de un diente inmaduro con periodontitis apical asintomática utilizando fibrina rica en plaquetas: informe preliminar. Canal Abierto[Internet]. 2011 sept [Consultado 14/12/2025]; (24): 32-37. Disponible en: https://investigadores.uandes.cl/es/publications/propuesta-de-un-modelo-para-lograr-la-revascularizaci%C3%B3n-pulpar-de/
14. Cámara Cabello D. Preservación de reborde alveolar con ingeniería tisular mediante fibrina rica en plaquetas: reporte de caso clínico. Rev Odontol Andes[Internet]. 2025 [Consultado 14/12/2025]; 2(1): 66-75. Disponible en: https://www.redalyc.org/articulo.oa?id=564660010006
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