Use of lasers in the treatment of periodontal disease
Keywords:
PERIODONCIA; REGENERACIÓN TISULAR GUIADA PERIODONTAL; TERAPIA POR LÁSER., PERIODONTICS; GUIDED TISSUE REGENERATION, PERIODONTAL; LASER THERAPY., PERIODONTIA; REGENERAÇÃO TECIDUAL GUIADA PERIODONTAL; TERAPIA A LASER.Abstract
Introduction: laser surgery has emerged as an adjuvant therapeutic alternative with the potential to optimize clinical periodontal outcomes.
Objective: to analyze the available scientific evidence on the use of laser therapy in the treatment of periodontal disease.
Methods: a systematic literature review was conducted in accordance with PRISMA guidelines. Electronic databases were consulted using a search algorithm that enabled the identification of existing sources. A selection process was carried out based on predefined inclusion and exclusion criteria, followed by an in-depth analysis of the studies that allowed for an adequate approach to the topic addressed.
Development: the analyzed literature describes the use of different types of lasers, including Er:YAG, Nd:YAG, diode, Er,Cr:YSGG, and InGaAsP, in both surgical and non-surgical therapies. The main findings indicate improvements in periodontal clinical parameters, such as reduced probing depth, gain in clinical attachment level, decreased bleeding on probing, and reduced subgingival bacterial load. Additionally, photothermal and biostimulatory effects have been reported, promoting wound healing and tissue regeneration.
Conclusions: laser surgery represents a promising adjuvant alternative in the management of periodontal disease, with potential benefits in inflammation reduction, bacterial control, and tissue regeneration. However, current evidence is not conclusive regarding its superiority over conventional therapies. Well-designed clinical studies with standardized protocols and long-term follow-up are required to more precisely define its effectiveness and clinical applicability.
Downloads
References
1. Lazureanu PC, Popescu FG, Stef L, Focsa M, Vaida MA, Mihaila R. The Influence of Periodontal Disease on Oral Health Quality of Life in Patients with Cardiovascular Disease: A Cross-Sectional Observational Single-Center Study. Medicina [Internet]. 2022 Apr 24 [cited 23/02/2023]; 58(5):584. Available from: https://www.mdpi.com/1648-9144/58/5/584/htm.
2. Kandhan TS, Rajasekar A. Prevalence of Periodontal Diseases Among Patients with And Without Systemic Diseases – A Retrospective Study. Journal of Complementary Medicine Research [Internet]. 2020 [cited 23/02/2023];11(4):155–155. Available from: https://www.bibliomed.org/mnsfulltext/55/55-1607666846.pdf?1766718864
3. Zheng M, Wang C, Ali A, Shih YA, Xie Q, Guo C. Prevalence of periodontitis in people clinically diagnosed with diabetes mellitus: a meta-analysis of epidemiologic studies. Acta Diabetologica. [Internet]. 2021 May 24 [cited 23/02/2023];58(10):1307–27. Available from: https://link.springer.com/article/10.1007/s00592-021-01738-2.
4. Yang Y, Liu S, Wang Y, Wang Z, Ding W, Sun X, et al. Changes of saliva microbiota in the onset and after the treatment of diabetes in patients with periodontitis. Aging (Albany NY) [Internet]. 2020 Jul 7 [cited 2023 Feb 23/02/2023];12(13):13090. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7377876/
5. Cuesta R, Pacheco Y. Las enfermedades orales en pacientes con diabetes mellitus tipo II. Conrado [Internet]. 2021 [cited 23/02/2023];17(79). Available from: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1990-86442021000200328.
6. Mera J. Prevalencia de enfermedad periodontal en pacientes adultos mayores con diabetes mellitus [Internet]. Universidad de Guayaquil; 2018 [cited 23/02/2023]. Available from: http://repositorio.ug.edu.ec/handle/redug/34077.
7. Rodas Avilés MG, Villavicencio Caparó E. PREVALENCIA DE AUTOPERCEPCIÓN DE LA ENFERMEDAD PERIODONTAL EN LA POBLACIÓN DE QUITO-ECUADOR,2021. Salud & Vida Sipanense [Internet]. 2021 Jan 5 [cited 19/06/2023];8(2):38–48. Available from: https://www.researchgate.net/publication/359275565
8. Funato A, Moroi H, Ogawa T. Regeneración ósea guiada asistida por raíces dentales con ligamento periodontal: Informes de casos de enfoques inmediatos y por fases para el tratamiento con implantes. Quintessence: Publicación internacional de odontología, [Internet]. 2022 [cited 23/02/2023];10(9):686–99. Available from: https://dialnet.unirioja.es/servlet/articulo?codigo=8764441&info=resumen&idioma=SPA
9. Polak D, Shapira L. An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes. J Clin Periodontol [Internet]. 2018 Feb 1 [cited 23/02/2023];45(2):150–66. Available from: https://pubmed.ncbi.nlm.nih.gov/29280184/
10. Graziani F, Karapetsa D, Mardas N, Leow N, Donos N. Surgical treatment of the residual periodontal pocket. Periodontol 2000 [Internet]. 29 Noviembre 2017 [cited 23/02/2023];76(1):150–63. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/prd.12156.
11. Mauri-Obradors E, Merlos A, Estrugo-Devesa A, Jané-Salas E, López-López J, Viñas M. Benefits of non-surgical periodontal treatment in patients with type 2 diabetes mellitus and chronic periodontitis: A randomized controlled trial. J Clin Periodontol [Internet]. 19 Deciembre 2017 [cited 23/02/2023];45(3):345–53. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/jcpe.12858.
12. Gheorghiu A, Franzen R, Arweiler NB, Ciurescu CE, Gutknecht N, Ciurescu VA, et al. Two-year outcomes following the adjunctive use of InGaAsP and Er,Cr:YSGG lasers in nonsurgical periodontal therapy in patients with stages III and IV periodontitis. Quintessence Int [Internet]. 2021 Oct 19 [cited 24/7/2023];52(10):848–61. Available from: https://pubmed.ncbi.nlm.nih.gov/34235909/
13. McCawley TK, McCawley MN, Rams TE. Immediate effect of Nd:YAG laser monotherapy on subgingival periodontal pathogens: a pilot clinical study. J Periodontal Implant Sci [Internet]. 2022 [cited 24/7/2023];52(1):1–11. Available from: https://pubmed.ncbi.nlm.nih.gov/35187875/
14. Chandra S, Shashikumar P. Diode Laser - A Novel Therapeutic Approach in the Treatment of Chronic Periodontitis in Type 2 Diabetes Mellitus Patients: A Prospective Randomized Controlled Clinical Trial. J Lasers Med Sci [Internet]. 2019 [cited 24/7/2023];10(1):56–63. Available from: https://pubmed.ncbi.nlm.nih.gov/31360370/
15. Zhu J, Wei R, Lv X, Qu C. Efficacy of a combined Er:YAG laser and Nd:YAG laser in non-surgical treatment for severe periodontitis. Lasers Med Sci [Internet]. 2022 Mar 1 [cited 24/7/2023];37(2):1095–100. Available from: https://pubmed.ncbi.nlm.nih.gov/34125321/
16. Akkarapatum A, Klanrit P, Sattayut S. Case Report: Interstitial-intralesional laser therapy and laser-assisted new attachment procedure for the treatment of alveolar bone loss provoked by an aggressive pyogenic granuloma. F1000Res [Internet]. 2022 Oct 7 [cited 24/7/2023];11:883. Available from: https://pubmed.ncbi.nlm.nih.gov/36111218/
17. Zhou X, Lin M, Zhang D, Song Y, Wang Z. Efficacy of Er:YAG laser on periodontitis as an adjunctive non-surgical treatment: A split-mouth randomized controlled study. J Clin Periodontol [Internet]. 2019 May 1 [cited 24/7/2023];46(5):539–47. Available from: https://pubmed.ncbi.nlm.nih.gov/31069833/
18. Dortaj D, Bassir SH, Hakimiha N, Hong H, Aslroosta H, Fekrazad R, et al. Efficacy of Nd:YAG laser-assisted periodontal therapy for the management of periodontitis: A double-blind split-mouth randomized controlled clinical trial. J Periodontol [Internet]. 2022 May 1 [cited 24/7/2023];93(5):662–72. Available from: https://pubmed.ncbi.nlm.nih.gov/34411291/
19. Talmac AC, Yayli NZA, Calisir M, Ertugrul AS. Comparing the efficiency of Er,Cr:YSGG laser and diode laser for the treatment of generalized aggressive periodontitis. Ir J Med Sci [Internet]. 2022 Jun 1 [cited 24/7/2023];191(3):1331–9. Available from: https://pubmed.ncbi.nlm.nih.gov/34263416/
20. Yukna RA. Clinical evaluation of Laser-Assisted New Attachment Procedure® (LANAP®) surgical treatment of chronic periodontitis: a retrospective case series of 1-year results in 22 consecutive patients. J Periodontal Implant Sci [Internet]. 2023 [cited 24/7/2023];53(3). Available from: https://pubmed.ncbi.nlm.nih.gov/36468483/
21. Katsikanis F, Strakas D, Vouros I. The application of antimicrobial photodynamic therapy (aPDT, 670 nm) and diode laser (940 nm) as adjunctive approach in the conventional cause-related treatment of chronic periodontal disease: a randomized controlled split-mouth clinical trial. Clin Oral Investig [Internet]. 2020 May 1 [cited 24/7/2023];24(5):1821–7. Available from: https://pubmed.ncbi.nlm.nih.gov/31410672/
22. Santonocito S, Polizzi A, Cavalcanti R, Ronsivalle V, Chaurasia A, Spagnuolo G, et al. Impact of Laser Therapy on Periodontal and Peri-Implant Diseases. Photobiomodul Photomed Laser Surg [Internet]. 2022 Jul 1 [cited 24/7/2023];40(7):454–62. Available from: https://pubmed.ncbi.nlm.nih.gov/35763842/
23. Chambrone L, Wang HL, Romanos GE. Antimicrobial photodynamic therapy for the treatment of periodontitis and peri-implantitis: An American Academy of Periodontology best evidence review. J Periodontol [Internet]. 2018 Jul 1 [cited 24/7/2023];89(7):783–803. Available from: https://pubmed.ncbi.nlm.nih.gov/30133749/
24. Theodoro LH, Marcantonio RAC, Wainwright M, Garcia VG. LASER in periodontal treatment: is it an effective treatment or science fiction? Braz Oral Res [Internet]. 2021 [cited 24/7/2023]; 35(Supp 2): 1–18. Available from: https://pubmed.ncbi.nlm.nih.gov/34586213/
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Verónica Alejandra Salame Ortiz

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Authors who have publications with this journal agree to the following terms: Authors will retain their copyrights and grant the journal the right of first publication of their work, which will be publication of their work, which will be simultaneously subject to the Creative Commons Attribution License (CC-BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.
Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g.: deposit it in an institutional telematic archive or publish it in a volume). Likewise, and according to the recommendations of the Medical Sciences Editorial (ECIMED), authors must declare in each article their contribution according to the CRediT taxonomy (contributor roles). This taxonomy includes 14 roles, which can be used to represent the tasks typically performed by contributors in scientific academic production. It should be consulted in monograph) whenever initial publication in this journal is indicated. Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which may produce interesting exchanges and increase citations of the published work. (See The effect of open access). https://casrai.org/credit/
