Use of endodontics and bone regeneration in the treatment of external root resorption: a clinical case report

Authors

Keywords:

ENDODONCIA; REGENERACIÓN ÓSEA; RESORCIÓN RADICULAR., ENDODONTICS; BONE REGENERATION; ROOT RESORPTION., ENDODONTIA; REGENERAÇÃO ÓSSEA; REABSORÇÃO RADICULAR.

Abstract

Introduction: external root resorption is a progressive dental pathology that compromises tooth stability and may lead to the loss of the affected organ, requiring an interdisciplinary approach.

Objective: to describe the therapeutic approach applied in a clinical case of external root resorption.

Case presentation: a 17-year-old male patient with a history of trauma to the upper left central incisor presented with pain during chewing and a vestibular fistula. Clinical examination revealed percussion sensitivity and local inflammatory signs, while tomography showed external root resorption and a diffuse bone lesion. Treatment included endodontic therapy with chlorhexidine irrigation, intracanal medication with calcium hydroxide, and obturation using Biodentine bioceramic. Subsequently, apical surgery was performed through a full-thickness flap, curettage of the lesion, and apical sealing with mineral trioxide aggregate. Bone regeneration was achieved using bovine-derived xenograft and a pericardial collagen membrane, followed by mattress sutures to ensure proper healing. Clinical and radiographic follow-up demonstrated symptom resolution, bone recovery, and adequate periradicular healing, confirming the effectiveness of the applied protocol.

Conclusions: the combination of endodontics, apical surgery, and bone regeneration proved to be an effective strategy for managing external root resorption. This approach promoted tissue repair and functional preservation of the tooth, highlighting the importance of early interventions and integrated protocols to optimize prognosis in young patients with traumatic history.

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References

. Manjushree R, Prasad K. Application of cone-beam computed tomography in the management of dilacerated maxillary central incisor associated with radicular cyst and external root resorption - A case report. J Conserv Dent JCD [Internet]. 2021[citado 22/12/2025]; 24(4):399-403. Disponible en: https://www.researchgate.net/publication/357804543

2. Parrales-Bravo C, Friedrichsdorf SP, Costa C, Paiva JB, Iglesias-Linares A. Does endodontics influence radiological detection of external root resorption? an in vitro study. BMC Oral Health [Internet]. 17 de abril de 2023 [citado 22/12/2025]; 23(1):221. Disponible en: https://www.researchgate.net/publication/370069912

3. Alves Otelakoski B, Magno Gonçalves F, Marques de Mattos de Araujo B, Zeigelboim BS, Veríssimo Meira Taveira K, Sampaio Santos R, et al. Comparison of orthodontic root resorption of root-filled and vital teeth: A meta-analysis. J Am Dent Assoc 1939 [Internet]. junio de 2022 [citado 22/12/2025]; 153(6):532-541.e7. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0002817722000216

4. Erdogan O, Casey S, Bahammam A, Son M, Mora M, Park G, et al. Radiographic Evaluation of Regenerative Endodontic Procedures and Apexification Treatments with the Assessment of External Root Resorption. J Endod [Internet]. 13 de junio de 2024 [citado 22/12/2025]; 50(10): 1420-1428. Disponible en: https://www.jendodon.com/article/S0099-2399(24)00345-5/abstract

5. Buchi-Velazquez A, Escobar-Torres D, Veloso V, Ferraro N. Clinical and radiographic characterization of external root resorption. Medwave [Internet]. 4 de abril de 2024 [citado 22/12/2025];24(3):e2780.Disponible en: https://www.medwave.cl/revisiones/revisiontemas/2780.html?_view=en

6. Korolenkova MV, Kharkova LY, Rakhmanova MS. [Pulp revascularization procedure for external inflammatory dental root resorption treatment]. Stomatologiia (Sofiia) [Internet]. 2024 [citado 22/12/2025] ;103(2):80-5. Disponible en: https://www.researchgate.net/publication/380592080

7. Zhao D, Xue K, Meng J, Hu M, Bi F, Tan X. Orthodontically induced external apical root resorption considerations of root-filled teeth vs vital pulp teeth: a systematic review and meta-analysis. BMC Oral Health [Internet]. 25 de abril de 2023 [citado 22/12/2025];23(1):241.Disponible en: https://www.researchgate.net/publication/370262135

8. Yoshpe M, Einy S, Ruparel N, Lin S, Kaufman AY. Regenerative Endodontics: A Potential Solution for External Root Resorption (Case Series). J Endod [Internet]. febrero de 2020 [citado 22/12/2025]; 46(2): 192-9. Disponible en: https://www.researchgate.net/publication/337788808

9. Mickeviciene L, Ciruliene V, Greta L. Long Term Outcome of Avulsed Immature Mandibular Incisor with Progressive External Root Resorption: 9 Years Follow-Up. J Oral Maxillofac Res [Internet]. 2023[citado 22/12/2025]; 14(2): e5. Disponible en: https://pubmed.ncbi.nlm.nih.gov/37521324/

10. Shi C, Mishina Y, Xu X, Miao L, Jiang L. Editorial: Basic research on bone development, bone homeostasis, and new strategies on bone regeneration. Front Physiol [Internet] .2023 [citado 22/12/2025]; 14:1285197. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC10541966/

11. Yudoh K, Sugishita Y, Suzuki-Takahashi Y. Bone Development and Regeneration 2.0. Int J Mol Sci [Internet]. 15 de mayo de 2023 [citado 22/12/2025];24(10):8761. Disponible en: https://www.mdpi.com/1422-0067/24/10/8761

12. Consolaro A, Cardoso M de A, Consolaro RB, Segato RAB. Canines and inflammatory external apical resorption in healthy maxillary lateral incisors due to occlusal trauma: when to detect the position of maxillary canines, to prevent it? Dent Press J Orthod [Internet]. 2022 [citado 22/12/2025]; 27(1): e22ins1. Disponible en: https://www.scielo.br/j/dpjo/a/zhh6bSQgmBqJJNJF9XHtbKQ/?format=html&lang=en

13. Gillman CE, Jayasuriya AC. FDA-approved bone grafts and bone graft substitute devices in bone regeneration. Mater Sci Eng C Mater Biol Appl [Internet]. noviembre de 2021 [citado 22/12/2025]; 130:112466. Disponible en: https://www.sciencedirect.com/science/article/pii/S0928493121006068

14. Tsukagoshi Y, Matsushita Y. Bone regeneration: A message from clinical medicine and basic science. Clin Anat N Y N. [Internet] septiembre de 2022. [citado 22/12/2025]; 35(6):808-19. Disponible en: https://www.researchgate.net/publication/361054310

15. Yang N, Liu Y. The Role of the Immune Microenvironment in Bone Regeneration. Int J Med Sci. [Internet] 2021. [citado 22/12/2025]; 18(16):3697-707. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC8579305/

Published

2025-12-23

How to Cite

1.
Morocho Segarra CV, Tobar-Peñaherrera AN, Cortés-Naranjo DG. Use of endodontics and bone regeneration in the treatment of external root resorption: a clinical case report. Rev Ciencias Médicas [Internet]. 2025 Dec. 23 [cited 2026 Jan. 3];29(1):e7003. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/7003

Issue

Section

CASE REPORTS