Multidisciplinary approach to guided tissue regeneration: report of a clinical case

Authors

Keywords:

ENFERMEDADES PERIODONTALES; PÉRDIDA DE HUESO ALVEOLAR; RECESIÓN GINGIVAL; REGENERACIÓN TISULAR GUIADA PERIODONTAL., PERIODONTAL DISEASES; ALVEOLAR BONE LOSS; GINGIVAL RECESSION; GUIDED TISSUE REGENERATION, PERIODONTAL., DOENÇAS PERIODONTAIS; PERDA DE OSSO ALVEOLAR; RECESSÃO GENGIVAL; REGENERAÇÃO TECIDUAL GUIADA PERIODONTAL.

Abstract

Introduction: bone and gingival loss represents a significant clinical challenge in dentistry due to its functional, esthetic, and periodontal implications, particularly in young patients undergoing orthodontic treatment.

Objective: to present the clinical outcomes of a multidisciplinary approach using guided tissue regeneration for the treatment of bone and gingival defects.

Case presentation: this report describes the case of a 22-year-old female patient who exhibited significant resorption of keratinized gingiva and the vestibular alveolar bone plate in the anteroinferior region, with marked root exposure. Following clinical and radiographic evaluation, a guided tissue regeneration procedure using a multidisciplinary approach was indicated. The surgical intervention included harvesting a palatal connective tissue graft and placing a xenogeneic particulate bone graft, followed by flap repositioning and suturing. The procedure was carried out under strict biosecurity measures and postoperative control. During the immediate follow-up, the patient showed adequate healing, minimal postsurgical symptoms, and stability of the treated tissues. The achieved regeneration restored the periodontal conditions necessary for the continuation of orthodontic treatment, improving oral function and esthetics.

Conclusions: guided tissue regeneration, when applied through a multidisciplinary approach, constitutes an effective therapeutic alternative for the recovery of lost periodontal tissues. Proper planning and execution promote satisfactory clinical outcomes, contributing to periodontal stability and improved patient quality of life.

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References

1. Abou Neel EA, Bozec L, Knowles JC, Syed O, Mudera V, Day RH, Hyun JK. Collagen — emerging collagen based therapies hit the patient. Adv Drug Deliv Rev [Internet]. 2013 [Citado 20/09/2025]; 65(4): 429–456. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0169409X12002542?via%3Dihub

2. Lu J, Wang Z, Zhang H, Xu W, Zhang C, Yang Y, et al. Bone graft materials for alveolar bone defects in orthodontic tooth movement. Tissue Eng Part B Rev[Internet].2022 [Citado 20/09/2025]; 28(1): 35–51. Disponible en: https://doi.org/10.1089/ten.TEB.2020.0212

3. Angulo-Serrano A, Quijandria-Briceño D, Alvarado-Menacho S. Rehabilitación integral de un paciente con reabsorción ósea horizontal, mediante regeneración ósea guiada simultánea a la colocación de implantes. Rev Estomatológica Hered [Internet]. 2018 [Citado 20/09/2025]; 28(2): 115. Disponible en: https://www.redalyc.org/journal/4215/421558077007/html/

4. Ramos-Pilco E, Condori Salinas Y, Antonio Alarcón M. Paladar o tuberosidad, ¿cuál es la mejor zona donadora para un injerto de tejido blando?: una revisión sistemática. Int J Odontostomat [Internet]. 2020 [Citado 20/09/2025]; 14(4): 602–609. Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1134546

5. Bacallao F, Bosch Pons M. Regeneración tisular guiada en pacientes portadores de periodontitis crónica del adulto. MediSur [Internet]. 2018 [Citado 20/09/2025]; 15(5): 623–628. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S1727-897X2017000500007

6. Bettin-Yanez DL, Lopez ZDC. Regeneración tisular guiada potencializada con fibrina rica en plaquetas en paciente con periodontitis agresiva generalizada. Reporte de un caso. CES Odontol [Internet]. 2021[Citado 20/09/2025]; 34(1): 125–135. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-971X2021000100125

7. Zarzuela M. Regeneración tisular guiada en defecto óseo de 3 paredes: enfermedad periodontal y oclusión. Rev Ateneo Argent Odontol [Internet].2016 [Citado 20/09/2025]; 55(1): 35–39. Disponible en: https://www.ateneo-odontologia.org.ar/articulos/lv01/articulo4.pdf

8. Valenzuela Ramos MRR, Ojeda Gómez R, Correia F. Regeneración ósea guiada (ROG): plasma rico en factores de crecimiento vs. autoinjerto dental particulado, revisión bibliográfica. Odontología Vital [Internet]. 2019 [Citado 20/09/2025]; 2: 45–52. Disponible en: https://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1659-07752019000200045

9. Morales Navarro D, Vila Morales D. Regeneración ósea guiada en estomatología. Rev Cubana Estomatol [Internet]. 2016 [Citado 20/09/2025]; 53(1): 67–83. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75072016000100008

Published

2025-12-31

How to Cite

1.
Villacis Tapia AF, Parra-Cabay KS, Logroño-Chávez VS, Albán-Pazmiño GC. Multidisciplinary approach to guided tissue regeneration: report of a clinical case. Rev Ciencias Médicas [Internet]. 2025 Dec. 31 [cited 2026 Feb. 14];29(1):e7013. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/7013

Issue

Section

CASE REPORTS