Changes provoked by antiretroviral therapy over some biochemical indicators of the nutritional status in people suffering from HIV/AIDS

Authors

  • Elisa Maritza Linares Guerra Licenciada en Bioquímica. Profesora Auxiliar. Universidad de Ciencias Médicas de Pinar del Río.
  • Everaldo Jerez Hernández Licenciado en Bioquímica. Instructor. Universidad de Ciencias Médicas de Pinar del Río.
  • Alina Pla Cruz Licenciada en Biología. Asistente. Universidad de Ciencias Médicas de Pinar del Río.
  • Nadia Acosta Nuñez Licenciada en Microbiología. Asistente. Universidad de Ciencias Médicas de Pinar del Río.
  • Miriam Hernández Alfonso Licenciada en Cultura Física. Asistente. Universidad de Ciencias Médicas. Pinar del Río.

Keywords:

HIV/drug effects, ALBUMIN/analysis, TRANSFERRIN/analysis.

Abstract

Aimed at determining the changes provoked by antiretroviral therapy (ARVT) over some biochemical indicators of the nutritional status in people suffering from HIV/AIDS an observational, analytic and cross-sectional study was carried out in Pinar de Rio Province. The study was comprised of 142 individuals, out of them 89 before receiving the ARVT (24 women and 65 men), and 53 undergoing ARVT. Serum of the patients was used to determine the concentrations of albumin, transferrin, glucose, creatinine, triglycerides, and total cholesterol using the computerized chemical analyzer HITACHI 902. Means of both groups of patients were compared through the Mann Whitney U Test. No differences were found in means obtained for serum albumin levels (p=0.141), transferrin (p=0.196) and glucose (p=0.59) when both groups were compared. Triglyceride levels and cholesterol significantly increased in the group of patients (HIV/AIDS) using antiretroviral therapy (1.29±0.82 vs. 1.98±1.49 [p=0.0004] for triglycerides and 3.95±1.03 vs. 4.55±1.15 [p=0.003] for cholesterol). It is concluded that ARVT diminishes the risk of malnutrition according to the biochemical indicators under study, but increases the risk of hyperlipemia.

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Published

2011-12-23

How to Cite

1.
Linares Guerra EM, Jerez Hernández E, Pla Cruz A, Acosta Nuñez N, Hernández Alfonso M. Changes provoked by antiretroviral therapy over some biochemical indicators of the nutritional status in people suffering from HIV/AIDS. Rev Ciencias Médicas [Internet]. 2011 Dec. 23 [cited 2025 Aug. 29];15(4):8-21. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/829

Issue

Vol. 15 No. 4 (2011)

Section

ORIGINAL ARTICLES

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