Central corneal thickness in juvenile glaucoma
Keywords:
Glaucoma/diagnosis, Eye diseases.Abstract
Introduction: juvenile glaucoma is an uncommon variety and its clinical manifestations can simulate a primary glaucoma of open angle.Objective: to assess the behavior of central corneal thickness in juvenile glaucoma.
Material and Method: an analytical, longitudinal and prospective study was carried out including 29 patients suffering from juvenile glaucoma who attended to the specialized center of Ophthalmology at “Pepe Portilla” children hospital, Pinar del Rio from June 2010 to December 2011. Results: the average age was 18, with a majority of male patients (51.72 %), and Caucasian, without statistical value. This figure (51.72 %) referred familial history of glaucoma; 93.10 % presented open angle glaucoma and 65.51% had a central corneal thickness inferior to 539 µm prevailing in this group a highly significant value of intraocular pressure between 22-25 mmHg was present in the 84.21% of them. No relationship was found between low-central corneal thicknesses and papillary-glaucoma alterations, a significant-statistical relationship among the values of intraocular pressure superior than 22mmHg and excavations greater than 0.5 with 92.85 % were found.
Conclusion: both sexes and races were equally affected prevailing patients suffering from open-angle glaucoma, family history was very important to establish the diagnosis; finding a significant association between the low corneal thickness and high figures of intra-ocular pressure not present in papillary glaucoma damage, which was related to high values of intra-ocular pressure.
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1. Turalba AV, Chen TC. Clinical and Genetic Characteristics of Primary Juvenile- Onset Open-Angle Glaucoma (JOAG). Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA. Seminars in Ophthalmology. [Internet] 2008 [Citado 8 de abril 2011]; 23(1): [Aprox. 6p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/18214788
2. Roche Caso S, Triana Casado I, Molina Cisneros C, Ricardo Lorenzo R, Cabezas García A. Caracterización del glaucoma juvenil. Rev Cubana Pediatr. [Internet] 2011 [Citado 8 de abril 2011]; 83(1). Disponible en:http://bvs.sld.cu/revistas/ped/vol83_1_11/ped04111.htm
3. Iviricu Tielves RJ, Correa Rojas O, De la Portilla Castro MM, Torres Paz Z, Martínez Rpdriguez R. Comportamiento del Glaucoma Juvenil. Enero-diciembre de 2007, Pinar del Río. CITMA Avances. 2008 Sept; 10(3).
4. Pfeiffer N, Torri V, Miglior S, Zeyer T, Adamsons I, Cunhan-Vaz J. Central corneal thickness in the European Glaucoma Prevention Study. Ophthalmology. [Internet] 2007 Sept [Citado 8 de abril 2011]; 114(3): [Aprox. 5p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/17126403
5. Gordon MO, Beiser JA, Brandt JD, Heuer DK, Higginbotham EJ, Johnson CA, et al. The Ocular Hypertension Treatment Study: Baseline Factors that Predict the Onset of Primary Open-angle Glaucoma. Arch Ophthalmol. [Internet] 2002 [Citado 8 de abril 2011]; 120(6): [Aprox. 6p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/12049575
6. Brown KE, Congdon NG. Corneal Structure and Biomechanics: Impact on the Diagnosis and Management of Glaucoma. Curr Opin Ophthalmol. [Internet]. 2006 [Citado 8 de abril 2011]; 17(4): [Aprox. 5p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/16900024
7. Díaz Alemán VT, Fernández-Banca Vaca G, Lozano López V, García Somalo M, Perera Sanz D, González M. Nomograma de Riesgo de Progreso de Hipertensión Ocular Basado en el Ocular Hypertension Treatment Study. Arch Soc Esp Oftalmol. [Internet]. 2005 [Citado 8 de abril 2011]; 80(3): [Aprox. 4p.]. Disponible en:http://scielo.isciii.es/scielo.php?pid=S0365-66912005000300005&script=sci_arttext
8. Saad BL, Ferreira C. Genética del Glaucoma Primario de Ángulo Abierto. [Internet]. Colombia [citado 8 Abr 2011]. Disponible en: http://med.javeriana.edu.co/publi/vniversitas/serial/v42n1/0012%20Genetica.PDF
9. Forsman E, Lemmela S, Varilo T, Kristo P, Forsius H, Sankila EM, et al. The role of TIGR and OPTN in Finnish glaucoma families: a clinical and molecular genetic study. Mol Vis. [Internet]. 2003 May-30 [Citado 8 de abril 2011]; 9: [Aprox.5p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/12789137
10. Pérez Z, Castillo A. Alteraciones gonioscópicas del ángulo camerular en el glaucoma juvenil. Revista Cubana de Oftalmologia. [Internet]. Ene-Jun 2008 [Citado 19 de junio de 2011]; 21(1): [Aprox. 7p.]. Disponible en:http://scielo.sld.cu/scielo.php?pid=S0864-21762008000100004&script=sci_arttext
11. Béjar F, Olivares D, Cantero MA, Sánchez D. Grosor corneal central determinado mediante topografía corneal ORBSCAN en pacientes diagnosticados con glaucoma en población mexicana. Rev Sanid Milit. [Internet]. 2007 [Citado 19 de junio de 2011]; 61(5): [Aprox. 9p.]. Disponible en: http://www.imbiomed.com.mx/1/1/articulos.php?method=showDetail&id_articulo=46836&id_seccion=88&id_ejemplar=4743&id_revista=16
12. Alías EG, Ferreras A, Polo V, Larrosa JM, Pueyo V, Honrubia FM. Importancia del espesor corneal central en el estudio de hipertensos oculares, sospechosos de glaucoma y glaucomas preperimétricos. Sociedad Española de Oftalmología. [Internet]. 2007 Oct [Citado 19 de junio de 2011]; 82(10). Disponiblñe en:http://scielo.isciii.es/scielo.php?pid=S0365-66912007001000005&script=sci_arttext
13. Hong S, Kim CY, Seong GJ, Hong YJ. Central corneal thickness and visual field progression in patients with chronic primary angle-closure glaucoma with low intraocular pressure. Am J Ophthalmol. [Internet]. 2007 [Citado 19 de junio de 2011]; 143(2): [Aprox. 1p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/17258538
14. Lopes JF, Wilson RP, Alvim HS, Shields CL, Shields JA, Calhoun J, et al. Central Corneal Thickness in Pediatric Glaucoma. Pediatr Ophthalmol Strabismus. [Internet]. March/april 2007 [Citado 19 de junio de 2011]; 44(2): [Aprox. 5p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/17410963
15. Hahn S, Azen S, Ying-Lai M, Varma R, Los Angeles Latino Eye Study Group. Central corneal thickness in Latinos. Invest Ophthalmol Vis Sci. [Internet]. 2003 [Citado 19 de junio de 2011]; 44(4): [Aprox. 4p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/12657586
16. Congdon NG, Broman AT, Bandeen-Roche K, Grover D, Quigley HA. Central corneal thickness and corneal hysteresis associated with glaucoma damage. Am J Ophthalmol. [Internet]. 2006 [Citado 19 de junio de 2011]; 141(5): [Aprox. 7p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16527231
17. Labrada Rodríguez YH, Flores Pérez D, González Hess L. Pesquisa de glaucoma juvenil en la provincia de Las Tunas. Estudio preliminar. Rev Cubana Oftalmol. [Internet]. 2002 jul-dic [citado 4 Nov 2011]; 15(1): [Aprox. 5p.]. Disponible en: http://bvs.sld.cu/revistas/oft/vol15_2_02/oft06202.htm
18. Tawara A, Inomata H. Developmental Inmaturity of the Trabecular MeshworI in Juvenile Glaucoma. Am J Ophthalmology. 1984; 98: 82-97.
19. Stewart WC, Day DG, Jenkins JN, Passmore CL, Stewart JA. Mean intraocular pressure and progression based on corneal thickness in primary open-angle glaucoma. J Ocul Pharmacol Ther. [Internet]. 2006 [Citado 19 de junio de 2011]; 22(1): [Aprox. 7p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16503772

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