Trend of cervical intraepithelial neoplasm grade- III and evolution of patients

Authors

  • Inalvis de la Caridad Cruz Hernández Univrsidad de Ciencias Médicas de Pinar del Río
  • Raydel Marrero Hernández Universidad de Ciencias Médicas de Pinar del Rio.
  • José Guillermo Sanabria Negrín Universidad de Ciencias Médicas de Pinar del Rio http://orcid.org/0000-0002-9599-636X
  • Rayza Hernández Díaz Universidad de Ciencias Médicas de Pinar del Río
  • Alenys Rivera Dopico Universidad de Ciencias Médicas de Pinar del Río

Keywords:

CERVIX UTERI /injuries/trends, UTERINE CERVICAL NEOPLASMS, PAPILLOMA.

Abstract

Introduction: the trend of grade-III cervical intraepithelial neoplasm and its impact on patients is unknown.

Objectives: to estimate the trend and evolution of grade-III cervical intraepithelial neoplasia (CIN III) in Pinar del Río during the period 2004-2014.

Method: two-stage study. First: observational, retrospective, cross-sectional to determine the annual incidence of injuries (CIN III) and second: the temporal trend of them, as well as the evolution of patients.

Results: the average annual incidence rate in women aged 15 years and over was 64.6x100 000 women, while in women involve in the screening program was 83.5x100 000. The difference between the concluding moment and the preliminary moment, it reported a annual increase of 27.6%. The average age for the diagnosis of CIN III-CIS was: 37.87 ± 10.6 years (range 15-81 years). Guane and Mantua were the municipalities with the highest incidence. More than 50% showed histological signs of HPV infection. The assessment of the edges involved in conization did not report cases of micro-invasive or invasive carcinoma. The lethality reported in these women was zero percent.

Conclusions: there is an increase in the detection of NIC III-CIS lesions. Guane and Mantua were the municipalities with the highest rates of incidence. The number of sexual partners and human papillomavirus infection are risk factors for the disease, not the age of cohabitation. The correct implementation of procedures has allowed no invasion or death to occur.

 

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Author Biographies

Inalvis de la Caridad Cruz Hernández, Univrsidad de Ciencias Médicas de Pinar del Río

Departamento de ciencias Básicas Biomédicas.  Especialista I Grado en Histología.  Prof. Asistente

Raydel Marrero Hernández, Universidad de Ciencias Médicas de Pinar del Rio.

Médico.  Especialista I Grado en Histología. Prof. Asistente. 

dpto.  Ciencias Básicas Biomédicas.

José Guillermo Sanabria Negrín, Universidad de Ciencias Médicas de Pinar del Rio

Médico. Especialista II Grado en Histología. Dr C Biológicas., Investigador Auxiliar, Prof. Consultante.

Adjunto del Departamento de Ciencias Básicas Biomédicas.

Rayza Hernández Díaz, Universidad de Ciencias Médicas de Pinar del Río

Especialista 1er Grado en MGI y en Histología, Profesor Aisstente

Alenys Rivera Dopico, Universidad de Ciencias Médicas de Pinar del Río

Especialista 1er grado en MGI, Residente de Anatomía Humana, Profesor Instructor

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Published

2018-07-05

How to Cite

1.
Cruz Hernández I de la C, Marrero Hernández R, Sanabria Negrín JG, Hernández Díaz R, Rivera Dopico A. Trend of cervical intraepithelial neoplasm grade- III and evolution of patients. Rev Ciencias Médicas [Internet]. 2018 Jul. 5 [cited 2025 Sep. 16];22(4):665-77. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/3442

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Section

ORIGINAL ARTICLES