Effectiveness of alternative treatment with topical oleozon in patients with onychomycosis

Authors

  • Juan Miguel Santaya-Labrador Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Río. Cuba. https://orcid.org/0000-0002-5760-9330
  • Eduardo Enrique Cecila Paredes Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Río. Cuba. https://orcid.org/0000-0002-0613-5075
  • Angel Echevarría-Cruz Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Río. Cuba. https://orcid.org/0000-0001-7589-000X
  • Elizabeth Cecilia-Paredes Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Río. Cuba. https://orcid.org/0000-0001-8423-432X

Keywords:

ONYCHOMYCOSIS, AGED, INTEGRATIVE MEDICINE.

Abstract

Introduction: onychomycoses are fungal infections of the nail plate and adjacent tissues.

Objective: to determine the efficacy of alternative treatment with topical oleozon in patients with onychomycosis of the 24th and 25th Doctor’s Offices belonging to Luis Augusto Turcios Lima University Polyclinic in Pinar del Rio province during 2017-2018. 

Methods: an observational, descriptive and cross-sectional study was conducted on patients diagnosed with onychomycosis in the 24th and 25th Doctor’s Offices belonging to Luis Augusto Turcios Lima University Polyclinic in Pinar del Rio province during 2017-2018.  The target group comprised 90 patients diagnosed with this disease, working with all of them, which were stratified into three groups, group-A (topical ketoconazole plus fluconazole tablet), group-B (topical oleozon) and group-C (fluconazole tablet plus topical oleozon).

Results: the age group 60-69 (31,1 %) and male sex (65,6 %) predominated, patients with nail discoloration changes predominated (32 %), in group-A 56,7 % of patients showed improvement between 3 and 6 months, group-B 93,3 % in the same period as group-A and in group-C 100 % were cured in the same period as the other groups.

Conclusions: the age group from 60-69 predominated, male sex was the most affected. The most frequent sign was discoloration change and the symptom was pain; combined treatment was the most effective.

Downloads

Download data is not yet available.

References

1. Insfrán Duarte LS, Meza Mariana Y, Monserrat Aldama MT, Aldama Olga M, Pereira Brunelli JG, Aldama Caballero BF et al. Características epidemiológicas de las onicomicosis en la consulta dermatológica. Rev. Nac. (Itauguá) [Internet]. 2019 Dic [citado 12/02/2020]; 11(2): 5-18. Disponible en : http://scielo.iics.una.py/scielo.php?script=sci_arttext&pid=S2072-81742019000200005&lng=en

2. Pérez Pico AM, Mingorance Álvarez E, Pérez Luque C, Mayordomo Acevedo R. Adquisición de competencias para el diagnóstico de onicomicosis mediante entrenamiento práctico podológico preclínico y clínico. Educ Med Super [Internet]. 2019 Dic [citado 12/02/2020]; 33(4): e1962. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=93466

3. Giniebra Marín GM, Rivera Rivadulla R, Gorrín Díaz Y, Linares Cánovas LP, Ordóñez Álvarez Lázaro Yoan. Onicomicosis, factores predisponentes, características y dermatosis asociadas. Rev Ciencias Médicas [Internet]. 2019 Jun [citado 12/02/2020]; 23(3): 380-386. Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1003780

4. Moreno Coutiño G. Onicomicosis en pacientes que viven con VIH/sida. Salud (i) Ciencia [Internet]. 2019 Abr [citado 12/02/2020]; 23(4): 1-2. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1667-89902019000100016&lng=es.

5. Eisman S, Sinclavir R. Diagnóstico y tratamiento de infecciones fúngicas ungueales. IntraMed. [Internet]. 2018 May [citado 12/02/2020]; 34(8): [aprox. 12p.]. Disponible: en: https://www.intramed.net/contenidover.asp?contenidoid=83632

6. Vega-Sánchez DC, Reyes-Pablo AE, Calderón-Pérez J, García-Valdez L, Fernández-Martínez RF, Arenas-Guzmán R. Micosis superficiales en pacientes embarazadas en un hospital general de segundo nivel de atención. Med. interna Méx. [revista en la Internet]. 2019 Feb [citado 12/02/2020]; 35(1): 16-19. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0186-48662019000100016&lng=es

7. Meza Aquino MY, Insfran Duarte LS, Aldama Negrete MM, Aldama Olmedo OM, Pereira Brunelli JG. Dermatofitos y hongos levaduriformes causantes de micosis superficiales de piel lampiña en un centro dermatológico, San Lorenzo-Paraguay. Rev. Nac. (Itauguá) [Internet]. 2019 Dec [citado 12/02/2020]; 11(2): 30-40. Disponible en : http://scielo.iics.una.py/scielo.php?script=sci_arttext&pid=S2072-81742019000200030&lng=en

8. Conejo Fernández A, Martínez Roig A, Ramírez Balza O, Álvez González F, Hernández Hernández A, Baquero Artigao F et al. Documento de consenso SEIP-AEPap-SEPEAP sobre la etiología, el diagnóstico y el tratamiento de las infecciones cutáneas micóticas de manejo ambulatorio. Rev Pediatr Aten Primaria [Internet]. 2016 Dic [citado 12/02/2020]; 18(72): e149-e172. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1139-76322016000400002&lng=es.

9. Vega-Sánchez DC, Reyes-Pablo AE, Calderón-Pérez J, García-Valdez L, Fernández-Martínez RF, Arenas-Guzmán R. Micosis superficiales en pacientes embarazadas en un hospital general de segundo nivel de atención. Med. interna Méx. [revista en la Internet]. 2019 Feb [citado 12/02/2020]; 35(1): 16-19. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0186-48662019000100016&lng=es

10. Giniebra Marín GM; Rivera Rivadulla R; Gorrín Díaz Y.Efectividad del Oleozón tópico en las Onicomicosis. I Jorn Cient de Farm y Sal 2021. [Internet] 2021. [citado 12/02/2020]; Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1283644

11. Stable- García Y, Zamora Rodríguez Z, Fernández García A. Efecto cicatrizante de los aceites ozonizados sobre lesiones de la piel. Rev. CENIC Cienc. Biol. [Internet]. 26 de mayo de 2021 [citado 12/02/2020]; 52(2):164-76. Disponible en: https://revista.cnic.edu.cu/index.php/RevBiol/article/view/913

12. Peña Rosell Amalia, Capote Femenías José Luis, Jover Capote Nadia. Utilidad del oleozón tópico en la gingivitis crónica fibroedematosa. Rev.Med.Electrón. [Internet]. 2019 Feb [citado 12/02/2020]; 41(1): 54-62. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=86309

13. Jiménez López Yadilenis, Matos Cantillo Dania Mavis, Pita Laborí Laura Yanet, de la Cruz Muguercia Marilyn, Matos Cantillo Carina Celia. Efectividad del Oleozón® tópico en la estomatitis subprótesis. Rev. inf. cient. [Internet]. 2018 Oct [citado 12/02/2020]; 97(5): 934-944. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=84039

14. Lecha M, y col. An open-label, multicentric study of the combination of amorolfine nail lacquer and oral itraconazole compared with oral itraconazole alone in the treatment of severe toenail onychomycosis. Current Therapeutic Research[Internet]. 2002. [citado 12/02/2020; 63(6)151: 366-379. https://www.sciencedirect.com/science/article/abs/pii/S0011393X02800406

15. Menéndez SA; Fernández MA; Amoroto ME; Uranga R; Acuña P; Elisa BJ; Díaz M. Eficacia y seguridad del oleozon tópico en el tratamiento de pacientes con impétigo. Rev panam. Infectol. [Internet]. 2007. [citado 12/02/2020]; 9(2): 23-29. Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/lil-516869

Downloads

Published

2022-07-03

How to Cite

1.
Santaya-Labrador JM, Cecila Paredes EE, Echevarría-Cruz A, Cecilia-Paredes E. Effectiveness of alternative treatment with topical oleozon in patients with onychomycosis. Rev Ciencias Médicas [Internet]. 2022 Jul. 3 [cited 2025 Oct. 13];26(3):e5514. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/5514

Issue

Vol. 26 No. 3 (2022)

Section

BRIEF COMMUNICATION

License

Authors who have publications with this journal agree to the following terms: Authors will retain their copyrights and grant the journal the right of first publication of their work, which will be publication of their work, which will be simultaneously subject to the Creative Commons Attribution License (CC-BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.

Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g.: deposit it in an institutional telematic archive or publish it in a volume). Likewise, and according to the recommendations of the Medical Sciences Editorial (ECIMED), authors must declare in each article their contribution according to the CRediT taxonomy (contributor roles). This taxonomy includes 14 roles, which can be used to represent the tasks typically performed by contributors in scientific academic production. It should be consulted in monograph) whenever initial publication in this journal is indicated. Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which may produce interesting exchanges and increase citations of the published work. (See The effect of open access). https://casrai.org/credit/