Syndrome of Lipodystrophy

Authors

  • Tamara González Gutiérrez Especialista de Primer Grado en Medicina General Integral. Máster en Enfermedades Infecciosas. Departamento provincial de Prevención y Control de las ITS/VIH/sida. Centro Provincial de Higiene, Epidemiología y Microbiología. Pinar del Río.
  • Omar Torres Crespo Especialista de Primer Grado en Medicina General Integral. Departamento Provincial de Prevención y Control de las ITS/VIH/sida. Centro Provincial de Higiene, Epidemiología y Microbiología. Pinar del Río.
  • Luis Vivas Bombino Especialista de Primer Grado en Medicina General Integral. Asistente. Dirección Municipal de salud. Pinar del Río.
  • Margarita González Tapia Especialista de Primer Grado en Medicina General Integral. Especialista de Segundo Grado en Higiene y Epidemiología. Instructora. Unidad municipal de Higiene y Epidemiología. Pinar del Río.

Keywords:

HIV-associated lipodystrophy syndrome, HIV, Highly active antiretroviral therapy, CD4-positive T-lymphocites.

Abstract

Introduction: HIV morbidity and mortality has substantially decreased with the use of HAART. The prevalence of lipodystrophy in HAART patients is greatly variable; clinically, the changes may be subtle at the beginning, with signs of central lipohypertrophy and peripheral lipoatrophy in early stages. When lipoatrophy affects the face and/or fat accumulates to the cervicodorsal region (buffalo hump), this is considered advanced lipodystrophy.
Clinical case: female patient of black race, 43 years of age, diagnosed HIV-positive in July 1999. After several years of treatment, changes started to be noticed in her body constitution, with clear signs of lipodystrophy.
Conclusions: the syndrome of lipodystrophy constitutes an adverse effect of HAART in AIDS patients, causing morphological and metabolic alterations that affects adherence to the treatment. Aesthetic repercussions provoke psychological alterations that affect these individuals directly in the affective, social and working areas. More research is needed for more evidence about this syndrome. The proper evaluation by health care professionals of HIV patients consuming HAART is vitally important, in order to timely diagnose the syndrome of lipodystrophy and apply fitting methods of treatments.

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References

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Published

2014-04-27

How to Cite

1.
González Gutiérrez T, Torres Crespo O, Vivas Bombino L, González Tapia M. Syndrome of Lipodystrophy. Rev Ciencias Médicas [Internet]. 2014 Apr. 27 [cited 2025 Aug. 30];18(2):320-8. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/1397

Issue

Vol. 18 No. 2 (2014)

Section

CASE REPORTS

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