Complications during the maintenance of real-organ donors in brain death

Authors

  • Yamilka Miranda Pérez Hospital General Docente Abel Santamaría Cuadrado
  • Alexanders García Balmaseda Hospital General Docente Abel Santamaría Cuadrado

Keywords:

Brain death, Maintenance, Tissue and organ procurement.

Abstract

Introduction: proper handling of potential donors before and after the diagnosis of brain death can improve the number and quality of the organs procured.

Objective: to learn about the complications of keeping real-organ donors in brain death at Abel Santamaria Cuadrado General Teaching Hospital during the years 2014 and 2015.

Material and Methods: a descriptive, cross-sectional prospective study in patients with the diagnosis of brain death who were admitted to the intensive care unit. Data were collected from the medical records; the target group included 36 patients with brain death and the sample was comprised of 15 real-donor patients.

Results: there was a predominance of male sex (66.67%), with the highest number of cases between 31 and 50 years of age. Hemorrhagic cerebrovascular disease was the cause that most contributed to the diagnosis of brain death with 73.33%, hypotension was present in all cases, hypernatremia and diabetes insipidus appeared in  73.33%, followed by hypokalemia (66.67%) and hypothermia (60%); extraction of organs was performed within the 4 - 8 hours after brain-death diagnosis in the 80% of real-donors.

Conclusions: awareness of the complications arising during the maintenance of real-organ donors is of vital importance, since it may adversely affect the viability of the organ to be transplanted; early identification and appropriate treatment must be improved in order to achieve the crucial goal, transplantation.

Downloads

Download data is not yet available.

Author Biographies

Yamilka Miranda Pérez, Hospital General Docente Abel Santamaría Cuadrado

Especialista de Primer Grado en Medicina Intensiva y Emergencias

Alexanders García Balmaseda, Hospital General Docente Abel Santamaría Cuadrado

Especialista de Primer Grado en Medicina Intensiva Y Emergencias. Coordinador Hospitalario de Donación y Trasplantes.

References

1.McKeown DW, Bonser RS, Kellum JA. Management of the heartbeating brain-dead organ donor. Br J Anaesth [Internet]. 2012 [citado 10 Nov 2015]; 108(Suppl-1): 96-107. Disponible en: http://bja.oxfordjournals.org/content/108/suppl_1/i96.full.

2. Querevalú Murillo W, Orozco Guzmán R, Díaz Tostado S. Mantenimiento del donante cadavérico en la Unidad de Terapia Intensiva. Revista de la asociación mexicana de medicina crítica y terapia intensiva [Internet]. 2013 Abr-Jun [citado 10 Nov 2015]; 27(2): 107-14. Disponible en: http://www.medigraphic.com/pdfs/medcri/ti-2013/ti132g.pdf

3. Dueñas Jurado JM. Protocolos clínicos de actuación ante el proceso de donación y extracción de órganos y tejidos para trasplante en donación en muerte encefálica. Cuad Med Forense [Internet]. 2015 Ene-Jun [citado 10 Nov 2015]; 21(1-2): 34-42. Disponible en: http://scielo.isciii.es/scielo.php?pid=S1135-76062015000100005&script=sci_arttext&tlng=en.

4.Bodí MA, Pont T, Sandiumenge A, Oliver E, Gener J, Badía M, et al. Potencialidad de donación de órganos en muerte encefálica y limitación del tratamiento de soporte vital en los pacientes neurocríticos. Med Intensiva [Internet]. 2015 [citado 10 Nov 2015]; 39(6): 337-44. Disponible en: http://linkinghub.elsevier.com/retrieve/pii/S0210569114002095?via=sd

5. Freire SG, Freire Silvério IL, Pinto Jales Menescal JT, Vasconcelos Quinidia de Lúcia Duarte de AQ, Torres De Vasconcelos G. Alterações fisiológicas da morte encefálica em potenciais doadores de órgãos e tecidos para transplanten. Esc Anna Nery Rev Enferm [Internet]. 2012 Out-Dez [citado 23 Jul 2015]; 16(4):. Disponible en: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1414-81452012000400017.

6. Fortuna Custodio JA, Rivera Marchena JR, Jiménez Lomas S, Morales Flores ME, Roldán García AM, Navarro Paz I, et al. Donación de órganos: metas del mantenimiento en el paciente con muerte encefálica. Revista de la Asociación Mexicana de Medicina Crítica y Terapia Intensiva [Internet]. 2014 Oct-Dic [citado 10 Nov 2015]; 28(4): 221-38. Disponible en: http://www.google.com.cu/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwikzdPZ-PnKAhXrmIMKHT_0CuAQFggfMAA&url=http%3A%2F%2Fnew.medigraphic.com%2Fcgi-bin%2Fresumen.cgi%3FIDARTICULO%3D52825&usg=AFQjCNElPyEMhh97HPGA_3nBE-UvO18Dcw&bvm=bv.114195076,d.amc

7. Escudero D, Valentín MO, Escalante JL, Sanmartín A, Perez-Basterrechea M, de Gea J, et al. Intensive care practices in brain death diagnosis and organ donation. Anaesthesia [Internet]. 2015 [citado 10 Nov 2015]; 70(10). Disponible en: http://onlinelibrary.wiley.com/doi/10.1111/anae.13065/full

8. Simas R, Kogiso Haruo D, Correia de Jesus C, Silva Ferraz da LF, Silva Azevedo I, Cruz Miranda Costa JW, et al. Influence of brain death and associated trauma on solid organ histological characteristicas. Acta Cir Bras [Internet]. 2012 Jul [citado 23 Jul 2015]; 27(7): [aprox. 9 p.]. Disponible en: http://www.scielo.br/scielo.php?pid=S0102-86502012000700006&script=sci_arttext

9. Sociedad argentina de terapia intensiva SATI. Terapia Intensiva. 5ta Ed. España: Editorial Médica Panamericana; 2015.

Published

2016-03-18

How to Cite

1.
Miranda Pérez Y, García Balmaseda A. Complications during the maintenance of real-organ donors in brain death. Rev Ciencias Médicas [Internet]. 2016 Mar. 18 [cited 2025 Sep. 14];20(1):27-32. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/2468

Issue

Section

ORIGINAL ARTICLES