Burkitt’s lymphoma: challenges in northern Nampula, Mozambique
Keywords:
Burkitt Lymphoma/pathology/etiology/mortality, Neoplasms.Abstract
Introduction: Burkitt's lymphomais a neoplasm with a high degree of malignancy; its clinical and histopathological features have not been previously described in Nampula, Mozambique.
Objective: to characterize Burkitt's lymphoma considering its clinical and histological features in Nampula, Mozambique, during the years 2012 and 2013.
Method: a descriptive, retroprospective study was carried out with a target group comprised of pediatric patients presenting tumor mass in cervical, facial, oropharyngeal and abdominal regions (N = 75) these patients attended the Central Hospital of Nampula, Mozambique, during the period 2012 to 2013. The sample included those patients diagnosed by fine-needle-aspiration biopsy and the status was confirmed by histological studies (n = 60). A computerized database was created collecting the data of the variables used, which were summarized by absolute and relative percentage frequencies.
Results: the highest frequency of cases were found in children under 6 years of both sexes, the mean time between the onset of symptoms and the pathological diagnosis was long, the largest group matched up 3 months and more; 31.6% of patients died, the most frequent cause was the impediment of admittance to the health services, malnutrition and treatment discontinuation.
Conclusions: early care and treatment are imperative to prevent the lethality of this disease, as well as providing accessibility to health care services for its opportune diagnosis all over the country.
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1. Bonet Fonseca I, Díaz Anaya A, Francis T, Fajardo Tornés YL. Linfoma de ovario. Rev Cubana ObstetGinecol [Internet]. 2012 Sep [citado 28 Dic 2015]; 38(3): 424-30. Disponible en: http://scieloprueba.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2012000300015&lng=es
2. Sierra Arego F, López Rodríguez CM. Linfoma de Burkitt. Rev Cubana Cir [Internet]. 2012 Mar [citado 28 Dic 2015]; 51(1): 96-104. Disponible en: http://scieloprueba.sld.cu/scielo.php?script=sci_arttext&pid=S0034-74932012000100013&lng=es
3 Rodrigues Pinto E, Gonçalves R, Fonseca E, MacedoG. Linfoma gastroduodenal de Burkitt en un paciente inmunocompetente. Rev Esp Enferm Dig [Internet]. 2013 Oct [citado 28 Dic 2015]; 105(9): 553-4. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082013000900007&lang=pt
4. Pérez Paz LE, Álvarez Morales F, García Fundora O, Hernández Flores A, Moreno González R, Llanes Gómez D. Linfoma de Burkitt. A propósito de un caso. Mediciego [Internet]. 2014 Dic [citado 28 Dic 2015]; 20(Supl- 2): Disponible en: http://www.revmediciego.sld.cu/index.php/mediciego/article/view/57/342
5.Gama Mascarenhas J, Araújo Júnior F, Villela Bolzan T, Gregórioa LC, Macoto Kosugi E. Nasopharyngeal Burkitt lymphoma as anearly AIDS manifestation. Braz J Otorhinolaryngol [Internet]. 2014 Sept-Dic [citado 28 Dic 2015]; 80(6): 546-8. Disponible en: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000600546&lang=pt
6.González Álvarez JR, Rodríguez Hernández MÁ, Cruz Cordero A, Rodríguez Hernández Z, Rodríguez Ramírez EA. Linfoma de Burkitt abdominal. Rev Ciencias Médicas [Internet]. 2014 Abr [citado 28 Dic 2015]; 18(2): 337-44. Disponible en: http://scieloprueba.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942014000200017&lng=es
7.Corti M, Villafañe MF, Valerga M, Sforza R, Bistmans A, Narbaitz M. Linfoma de Burkitt primario de la cavidad oral en una paciente con sida. Reporte de un caso y revisión de la literatura. Rev Esp Cirug Oral y Maxilofac [Internet]. 2015 Ene-Mar [citado 28 Dic 2015]; 37(1):. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-05582015000100008&lang=pt
8. Budiongo AN, Ngiyulu RM, Lebwaze BM, Gini-Ehungu JL, Mafuta EM, Ekulu PM, et al. Pediatric non-Hodgkin lymphomas: first report from Central Africa. Pediatr Hematol Oncol [Internet]. 2015 May [citado 28 Dic 2015]; 32(4): 239-49. Disponible en: http://www.tandfonline.com/doi/abs/10.3109/08880018.2015.1013231
9. Dinand V, Sachdeva A, Datta S, Bhalla S, Kalra M, Wattal C, et al. Plasma Epstein Barr virus (EBV) DNA as a biomarker for EBV associated Hodgkin lymphoma. Indian Pediatr [Inetrnet]. 2015 Aug [citado 28 Dic 2015]; 52(8): 681-5. Disponible en: http://link.springer.com/article/10.1007/s13312-015-0696-9
10. Ding J, Wang LX, Zhao XL, Wang LJ, Li DD, Yao YS, et al. Clinical Analysis of 41 Patients with Burkitt's lymphoma. Zhongguo Shi Yan Xue Ye Xue Za Zhi [Internet]. 2015 Apr [citado 28 Dic 2015]; 23(2): 425-30. Disponible en: http://europepmc.org/abstract/med/25948198
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