Epidemiological clinic of newborns with thrombocytopenia

Authors

  • Helen Abascal González Hospital General Docente: Abel Santamaría.
  • Nuvia Suárez García Hospital General Docente: Abel Santamaría.
  • Meylin Hernández Castro Hospital General Docente Abel Santamaría.

Keywords:

THROMBOCYTOPENIA, NEWBORN INFANT, PREMATURE INFANT.

Abstract

Introduction: many of the entities and / or clinical conditions in neonatology have some degree of thrombocytopenia.

Objective: to characterize clinically and epidemiologically newborns with thrombocytopenia.

Method: an observational, descriptive and cross-sectional study was carried out in the Neonatology service, General Teaching Hospital "Abel Santamaría Cuadrado" of Pinar del Río, Cuba, from 2011 to 2015. The universe consisted of infants admitted to the of neonatal intensive care unit (N = 519) and the intentional sample were those diagnosed for thrombocytopenia (n = 97). Statistical processing was based on Descriptive Statistics methods.

Results: of the total number of newborns admitted to the neonatal intensive care unit, 18.7% developed thrombocytopenia, which had a linear behavior in the course of the years without any differences in their distribution according to sex. In neonates with thrombocytopenia, a predominance of moderate prematurity (30-33.6 weeks) was found, with 38.1%. More than half of the cases (63.9%) occurred in the first 72 hours of life (precocious) with a predominance in newborns with intrauterine growth retardation (16.5%). In most of the morbidities developed by neonates, mild thrombocytopenia (49.5%) and moderate (38.1%) predominated according to severity. 

Conclusion: the presence of thrombocytopenia according to its different degrees of severity and time of onset is a decisive indicator in the orientation of the diagnosis and treatment of the great majority of serious morbidities present in the neonatal stage.

 

 

 

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Author Biographies

Helen Abascal González, Hospital General Docente: Abel Santamaría.

Especialista de Primer Grado en Neonatología.

Nuvia Suárez García, Hospital General Docente: Abel Santamaría.

Especialista Ier grado en Neonatología. Dr. Msc. en Atención Integral al niño. Asistente

Meylin Hernández Castro, Hospital General Docente Abel Santamaría.

Especialista de Primer Grado en Neonatología

References

1. Sola A. Descubriendo las necesidades del recién nacido con trombocitopenia. En: Cuidados Neonatales. Segunda Edición: Tomo I. Buenos Aires: Editora Científico Interamericana; 2011. p. 600-6118.

2. Sonam S. Nandyal, et al. Study of thrombocytopenia in neonatal intensive care unit. Indian Journal of Pathology and Oncology [Internet]. 2016, Mar [citado 03 Mar 2017]; 3(1):55-59. Disponible en: https://www.innovativepublication.com/admin/uploaded_files/IJPO_3%281%29_55-59.pdf

3. Arif SH, Ahmad I, Ali SM, Khan HM. Thrombocytopenia and Bacterial Sepsis in Neonates. Indian J Hematol Blood Transfus[Internet]. 2012, Mar [citado 03 Mar 2017]; 28(3):147-15. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422386/pdf/12288_2011_Article_118.pdf

4. Amutha J., et al. Study of neonatal thrombocytopenia etiology, clinical profile, immediate outcome and short term follow up of neonatal thrombocytopenia. International Journal of Current Medical And Pharmaceutical Research [Internet]. 2016, Oct [citado 27 Feb 2017]; 2(10):828-830. Disponible en: http://journalcmpr.com/sites/default/files/issue-files/CMPR-A-0317.pdf

5. Martínez M. Bleeding complications in newborns. XII Congreso del Grupo CAHT [Internet]. 2016, Sep [citado 15 Ene 2017]; 20(Ext):67-71. Disponible en: http://www.sah.org.ar/revista/numeros/08-vol-20-congre-2016.pdf

6. Cremer M, et al. Thrombocytopenia and platelet transfusion in the neonate [Abstract]. Red Latinoamericana de Pediatría y Neonatología [Internet]. 2016, Feb [citado 15 Ene 2017]; 21(1):10-18. Disponible en: https://relaped.wordpress.com/2016/03/04/trombocitopenia-neonatal-y-la-transfusion-de-plaquetas/

7. Villena Galarza, M. V. (2013, June 10). “Influencia de la preeclampsia en la restricción del crecimiento intrauterino en los recién nacidos ingresados en el servicio de neonatología del hospital iess ambato en el período enero - agosto 2012.” Retrieved from http://repositorio.uta.edu.ec/jspui/handle/123456789/3834

8. Ramesh Bhat Y. Neonatal thrombocytopenia and pregnancy induced hypertension. Siicsalud [Internet]. 2013, Sep [citado 15 Ene 2017]; 20:270-273. Disponible en: http://www.siicsalud.com/sic203/pdf/127021.pdf

9. Fustolo-Gunnink, et al. Early-Onset Thrombocytopenia in Small-For-Gestational-Age Neonates: A Retrospective Cohort Study. PLoS ONE [Internet]. 2016, May 11(5): e0154853. http://dx.doi.org/10.1371/journal.pone.0154853

10. Mesquita Mirta, et al. Predictive Value of the Complete Blood Count (CBC) in Neonatal Sepsis. Pediatr. (Asunción) [Internet]. 2011, Abr [citado 15 Ene 2017]; 38(1):23-30. Disponible en: http://scielo.iics.una.py/pdf/ped/v38n1/v38n1a05.pdf

11. Fernanda Cofré, et al. TORCH syndrome: Rational approach of pre and post natal diagnosis and treatment. Recommendations of the Advisory Committee on Neonatal Infections Sociedad Chilena de Infectología, 2016. Rev Chilena Infectol [Internet]. 2016 [citado 15 Ene 2017]; 33(2):191-216. Disponible en: http://www.scielo.org.ar/pdf/aap/v113n3/v113n3a15.pdf

12. Nora Sordelli, et al. Symptomatic cytomegalovirus infection through breastfeeding in a 45 days old boy. Arch Argent Pediatr [Internet]. 2015 [citado 15 Ene 2017]; 113(3):e145-e148. Disponible en: http://www.scielo.cl/pdf/rci/v33n2/art10.pdf

13. Maria Teresa Mella, et al. Neonatal alloimmune thrombocytopenia. International Journal of Clinical Transfusion Medicine [Internet]. 2015, Jun [citado 15 Ene 2017]; 2015(3): 29-40. Disponible en: https://doi.org/10.2147/IJCTM.S51926

14. Elena Martínez-Cuevas, et al. Trombocitopenia aloinmune del feto y el neonato: a propósito de 2 casos. Rev Electron Biomed [Internet]. 2014 [citado 15 Ene 2017]; 2014(3): 33-38. Disponible en: http://biomed.uninet.edu/2014/n3/martinezcuevas.html

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Published

2017-06-01

How to Cite

1.
Abascal González H, Suárez García N, Hernández Castro M. Epidemiological clinic of newborns with thrombocytopenia. Rev Ciencias Médicas [Internet]. 2017 Jun. 1 [cited 2025 Aug. 29];21(3):312-8. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/3034

Issue

Vol. 21 No. 3 (2017)

Section

ORIGINAL ARTICLES

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