Early stages of Laryngeal Cancer

Authors

Keywords:

CANCER CARE FACILITIES, NEOPLASMS, LARYNGEAL NEOPLASMS /drug therapy, EARLY DIAGNOSIS, SURVIVORSHIP.

Abstract

Introduction:  laryngeal cancer is diagnosed with the highest incidence at an early stage, it represents the second most common cause of malignant neoplasms of the respiratory tract after lung cancer, its diagnosis and effective treatment to reduce morbidity and mortality is of vital importance.

Objective: to describe the results obtained in the management of patients with laryngeal cancer in early stages.

Methods: a retrospective, descriptive study was conducted at the National Institute of Oncology and Radiobiology, from January 1, 2005 to December 31, 2009. The study population consisted of all patients with early-stage squamous cell carcinoma of the larynx. All clinical history information was collected and the results were recorded on the data collection sheet.

Results: male gender predominance was found in the series studied (86,5 %) and the age group of 60 years (64,5 %) and older. It was found that more than half of the cases had a history of smoking and alcoholism (71,3 %). Dysphonia was the main reason for consultation (96,8 %). The most affected anatomical site was the glottis (87.6 %) and the well-differentiated histological variety predominated with 58,2 %. Stage-I was 61,4 %. 78,5 % of the patients received radiotherapy as the only modality.

Conclusions: the socio-demographic and therapeutic variables of the patients in this series are similar to those reported by other authors. When comparing it with national and international series. 

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Author Biographies

Lucien Bory Porra, Universidad de Ciencias Médicas de Pinar del Rio. Centro oncológico provincial III Congreso. Pinar del Río, Cuba

Médico, Esoecialista primer grado en Oncología y Radiobiología

Yamilka Sánchez Azcuy, Universidad de Ciencias Médicas de Pinar del Rio. Centro oncológico provincial III Congreso. Pinar del Río, Cuba

Especialista de primer grado en Oncología y Radiobiología. Aspirante a Investigador. Asistente

Roberto Ortiz Benet, Universidad de Ciencias Médicas de la Habana. Hospital Manuel Fajardo. La Habana, Cuba

Especialista de primer grado en Oncología y Radiobiología.

Jorge Milian Baldor, Universidad de Ciencias Médicas de Pinar del Rio. Centro oncológico provincial III Congreso. Pinar del Río, Cuba

Especialista de primer grado en Oncología y Radiobiología. Asistente

Keilan María Pérez Hernández, Universidad de Ciencias Médicas de Pinar del Rio. Centro oncológico provincial III Congreso. Pinar del Río, Cuba

Especialista de primer grado en Medicina General Integral

References

1. García-Sáncheza M, Romero-Duránb E, Mantilla-Moralesb A, Gallegos-Hernándezb JF. Laringectomía subtotal supracricoidea. La importancia del análisis histopatológico. Gaceta Mexicana de Oncología [Intenet] 2014 [Citado 20/05/2018]; 13(3): [aprox. 5p.]. Disponible en: http://www.medigraphic.com/pdfs/actmed/am-2014/am143c.pdf

Consultado en junio de 2014. www.sinais.salud.gob.mx. 2008.

2. Choong N, Vokes E. Expanding Role of the Medical Oncologist in the Management of Head and Neck Cancer. CA Cancer J Clin. [Intenet] 2008 [Citado 20/05/2018]; 58: [aprox. 20p.]. Disponible en: https://onlinelibrary.wiley.com/doi/pdf/10.3322/CA.2007.0004

3. Ram Chang A, Wu HG, Pack CH, Kyung Jeon Y, Kim CW.Expression of Epidermal Growth Factor Receptor and Cyclin D1 in Pretreatment Biopsies as a Predictive Factor of Radiotherapy Efficacy in Early Glottic Cancer. Head & Neck. [Intenet] 2008 [Citado 20/05/2018]; 30 (7): [aprox. 5p.]. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1002/hed.20788

4. Jatin S. Cirugía y Oncología de Cabeza y Cuello. 3ra edition; 2004.p. 268-270.

5. Colmenarejo R, Menendez PC, Garcia JL. Cáncer de Laringe. In: Cortés Funes H, Colomer R. Tratado de Oncología. 2da Ed. 2009; 58:169-190.

6. Mendehall WM, Werning JW, Hinerman RW, et al . Management of T1-T2 Glottic Carcinomas. Cancer. [Intenet] 2004 [Citado 20/05/2018]; 100: [aprox. 6p.].Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1002/cncr.20181

7. Mena Canata C, Osorio M, Amarilla P, González J, Bozano J. Resultados de las laringectomías conservadoras en el carcinoma de laring. An. Fac. Cienc. Méd [Intenet] 2014 [Citado 20/05/2018]; 47(2): [aprox. 18p.]. Disponible en: http://scielo.iics.una.py/pdf/anales/v47n2/v47n2a02.pdf

8. Tobacco smoke and involuntary smoking.IARC Monogr Evol Carcinog Risks Hum [Intenet] 2004 [Citado 20/05/2018]; 83. [aprox. 20p. ]. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/15285078

9. Ramos Aguerri A. Manual Práctico de Oncología Radioterápica. Madrid: SEOR; 2013.p.1-429. Disponible en: http://www.seor.es/wp-content/uploads/Manual-Practico-de-Oncolog%C3%ADa-Radioterapica.pdf.

10. Soon-Hyun A, Hyun Jun H, Soon Young K, Kee Hwan K, Jong-Lyel R, Junsun R, et al. Guidelines for the Surgical Management of Laryngeal Cancer: Korean Society of Thyroid-Head and Neck Surgery. Clinical and Experimental Otorhinolaryngology [Intenet] March 2017 [Citado 20/05/2018]; 10(1): [aprox. 43p.]. Disponible en:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327593/pdf/ceo-2016-01389.pdf

Published

2019-06-05

How to Cite

1.
Bory Porra L, Sánchez Azcuy Y, Ortiz Benet R, Milian Baldor J, Pérez Hernández KM. Early stages of Laryngeal Cancer. Rev Ciencias Médicas [Internet]. 2019 Jun. 5 [cited 2025 Oct. 13];23(4):553-61. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/3912

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Section

ORIGINAL ARTICLES