Factors related to longitudinal changes in body fat in people with HIV/AIDS

Authors

Keywords:

BODY MASS INDEX, ANTI-RETROVIRAL AGENTS/Treatment, ADIPOSITY, ACQUIRED IMMUNODEFICIENCY SYNDROME, PATIENT.

Abstract

Introduction: despite antiretroviral treatment (ART) and its current wide coverage, HIV/AIDS continues as an increasing health problem, and with it, alterations in body composition.

Objective: to assess the influence of individual factors, HIV and ART, on the longitudinal changes in body fat in people with HIV/AIDS.

Methods: longitudinal-retrospective study that included the data of 159 HIV/AIDS people from Pinar del Río, Cuba, (72.3% men) with at least three determinations of body mass index, tricipital skin-fold thickness, waist and hip circumference, over a period of 1.3 years. Longitudinal models with two levels were estimated using multilevel regression for repeated measurements.

Results: only waist circumference and waist-to-hip ratio (WHR) showed significant longitudinal changes (p<0.001). Sex, time with ART and the initial WHR were the predictor variables that contributed significantly (p<0.1) to the increase of the WHR in the regression models.  Male sex contributed with an increase of 4.2% to the waist-to-hip ratio (WHR). For each year with antiretroviral treatment the WHR increased by 0.63% and the WHR that the individuals had at the end of the study represented 78.1% of the initial WHR plus a constant value of 20%.

Conclusions: the indicators of the central abdominal fat were the most useful to estimate the longitudinal changes of body fat index in HIV/AIDS individuals, the initial WHR was the best predictor of this indicator at the end of the follow-up period.

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Author Biographies

Elisa Maritza Linares Guerra, Universidad de Pinar del Río Hermanos Saiz Montes de Oca, Pinar del Río, Cuba

Profesora Titular e Investigadora del Centro de Estudios de Medio Ambiente y Recursos Naturales de la Universidad de Pinar del Río

María Amparo León Sánchez, Universidad de Pinar del Río Hermanos Saiz Montes de Oca, Pinar del Río, Cuba

Ingeniera Industrial. Profesora Titular de Matemática. 

Sergio Santana Porbén, Hospital Pediátrico Docente “Juan Manuel Márquez”. La Habana. Cuba.

Especialista de Segundo Grado en Bioquímica Clínica. Máster en Nutrición en Salud Pública. Profesor Asistente de Bioquímica.

Tamara González Gutiérrez, Jefa del Programa Municipal de Prevención y Control de las ITS/VIH/sida. Pinar del Río. Cuba.

Especialista de Primer Grado en Medicina General Integral y Segundo Grado en Higiene y Epidemiología. Investigador Agregado.

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Published

2019-12-13

How to Cite

1.
Linares Guerra EM, León Sánchez MA, Santana Porbén S, González Gutiérrez T. Factors related to longitudinal changes in body fat in people with HIV/AIDS. Rev Ciencias Médicas [Internet]. 2019 Dec. 13 [cited 2025 Sep. 20];24(1):e4147. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/4147

Issue

Vol. 24 No. 1 (2020)

Section

ORIGINAL ARTICLES

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