Physical mechanisms involved in cardiovascular damage of the COVID-19 carriers
Keywords:
CARDIOVASCULAR DISEASES, CORONAVIRUS INFECTIONS/physiopathologyAbstract
Introduction: COVID-19 is a new disease which provokes damage to human health, with direct impact on the cardiovascular system.
Objective: to describe the pathophysiogenic mechanisms involved in the cardiovascular damage in COVID-19 patients.
Method: a literature review was carried out, through articles retrieved in PubMed, SciELO, EBSCO and ClinicalKey, using 27 references.
Development: different pathophysiogenic mechanisms are associated with cardiovascular damage in COVID-19 patients; among them direct myocardial injury, viral invasion of cardiomyocytes, alteration of myocardial supply-demand index, atheroma-plaque rupture and coronary thrombosis, systemic inflammation and electrolyte imbalances.
Conclusions: determining the mechanisms involved in cardiovascular damage is a fundamental pillar as a preventive and screening strategy in COVID-19 patients. Inflammatory response, secondary hemodynamic changes to the viral process, as well as hypoxemia, are mechanisms of negative impact on cardiovascular health, leading to the development of acute cardiac injury.
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