Study of uncertainties in radiotherapy to prostate cancer patients with cone-beam computed tomography on a day-to day basis
Keywords:
PROSTATIC NEOPLASMS, ADENOCARCINOMA, RADIOTHERAPY SETUP ERRORS, TOMOGRAPHY, X-RAY COMPUTED, PATIENT.Abstract
Introduction: radiations with therapeutic aims have revolutionized medicine, particularly radiation technologies for the treatment of cancer.
Objective: to determine the margin of errors of the configuration and the movement of organs in determining the position of Clinical Target Volume using kilovoltage cone-beam computed tomography in the treatment of prostate cancer, as well as to quantify the movement of organs during the planned therapy of prostate obtained by a margin for the prostate.
Methods: an experimental research, the radio-therapeutic method on a day-to day basis was taken on. Patients registered from January to April 2017 on Cancer Radiotherapy from the University Hospital of Verona University in Italy, with prostate adenocarcinoma stages T1 to T4; and who were treated using volumetric modulated arch therapy.
Results: making use of Van Herk’s formula to position the margin of prostate, it was observed that in the craniocaudal and lateral direction there are small scatterings, and in the anteroposterior direction the degree of scattering is greater, being related to rectal filling, bladder movement and peristalsis of the patient. Finding the required margins for the prostate between CTV and PTV would be in the craniocaudal direction 3,3 mm, lateral 3,7 mm and anteroposterior 4,4 mm.
Conclusions: cone-beam computed tomography is a precise tool to guide the images; it provides an equivalent approach of correction of the configuration for prostate cancer patients.
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