Evolution of periodontal bone defects treated with platelet-rich plasma
Keywords:
PERIODONTICS, PLATELET-RICH PLASMA, BONE REGENERATION, REGENERATIVE MEDICINE.Abstract
Introduction: bioactive factors, including platelet concentrates, are used as therapy for the repair and healing of periodontal tissues due to their regenerative potential.
Objective: to evaluate the evolution of periodontal bone defects treated with platelet-rich plasma, in patients with periodontitis, in Santiago de Cuba, during the period 2017-2019.
Methods: a prospective longitudinal study was conducted in Santiago de Cuba, from December 2017 to December 2019, in patients of both sexes, between 30 and 59 years old, with a diagnosis of periodontitis requiring surgical treatment, choosing a sample of 45 patients presenting at least one site with periodontal intra-osseous defects, 4 or more millimeters deep, who met the diagnosis and criteria for using Platelet-Rich Plasma. Clinical, radiographic and response variables were used, expressed in absolute/relative frequencies and arithmetic mean, with standard deviation and t-test validation.
Results: the 93,3 % of the cases achieved clinical signs of normality of the operated soft tissue at 7 days. Bleeding on probing at six months of evolution persisted in only 4,4 % of the cases. The comparison of mean tooth mobility, probing depth and clinical insertion loss before and after treatment decreased significantly.
Conclusions: the evolution of periodontal parameters evaluated in bone defects after the application of platelet-rich plasma as part of the surgical treatment of periodontitis was satisfactory in almost the totality of the patients, with clinical improvement.
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