Evaluation of cosmetic results of the nasal ala, dorsum and tip of the nose in treatments with SENSUS SRT-100TM

Authors

Keywords:

CARCINOMA, BASAL CELL, RADIOTHERAPY, SKIN, OLFACTORY MUCOSA.

Abstract

Introduction: non-melanoma skin cancer (NMSC) is the most common cancer in humans. Surgery in these patients has been considered the "gold standard", but it may not be the appropriate option, especially in areas where it may cause functional or cosmetic morbidities due to tissue loss.

Objective: To evaluate cosmetic outcomes in patients with skin carcinomas in the nasal ala, dorsum and/or tip of the nose treated with surface radiotherapy.

Methods: an observational, longitudinal, retrospective study was conducted in patients with skin carcinoma treated with superficial radiotherapy with SENSUS SRT-100 TM during the period September 2017 to December 2021 in Pinar del Río. The universe consisted of 34 patients, the sample consisted of 28, obtained by non-probabilistic purposive sampling according to the established inclusion and exclusion criteria.

Results: the average age recorded was over 60 years, male gender, skin colour white and the predominant histological type was basal cell carcinoma. Conventional fractionation schedules were used in more than 70 % of cases. The most frequent late adverse effects were mild atrophy of the nasal cartilage and hypopigmentation of the skin, classified as toxicity grade 0/1 linked to an excellent/good cosmetic outcome in 89,7 %.

Conclusions: The cosmetic results obtained were considered excellent/good, reporting low toxicity profile and low local recurrence rates, demonstrating safety and quality through the use of surface radiotherapy as a treatment option in patients with skin carcinomas.

Downloads

Download data is not yet available.

References

1. Mark SN, et al. ConSENSUS Guidelines on the use of superficial radiation therapy for treating nonmelanoma skin cancers and keloids. J Clin Aesthet Dermatol [Internet]. 2019 [citado 20/05/2019]; 12(2): 12–18. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415702

2. Fahradyan A, Howell AC, Wolfswinkel EM, Tsuha M, Sheth P, Wong AK. Updates on the Management of Non-Melanoma Skin Cancer (NMSC). Healthcare [Internet]. 2017 [citado 20/05/2019]; 5(4): 82. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746716/

3. Apalla Z, Lallas A, Sotiriou E, Lazaridou E, Ioannides D. Epidemiologicaltrends in skincancer. DermatolPract Concept [Internet].2017 [citado 20/05/2019]; 7(2): 1-6. Disponible en: https://pdfs.semanticscholar.org/45c9/e2d142305478a6612a179ab9ac6905e733c0.pdf?_ga=2.247170439.202137144.1571040317-239534662.1568882910

4. Anuario estadístico de salud. 2018. Ministerio de Salud Pública, Dirección de registros médicos y estadísticos de salud. [Internet] La Habana; 2019 [citado 20/05/2019]. Disponible en: http://files.sld.cu/bvscuba/files/2019/04/Anuario-Electr%C3%B3nico-Espa%C3%B1ol-2018-ed-2019-compressed.pdf

5. Marcasciano M, et al. Surgical treatment with locorregional flap for the nose. Biomed Res Int [Internet]. 2017 [citado 20/05/2019]; 2017: 9750135. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757109/

6. Simone G, Giuseppe C, Pietro S, Bellieni A, Lodovico B, Cho William C, et al. Skin Cancer Epidemics in the Elderly as An Emerging Issue in Geriatric Oncology. Aging and Disease [Internet]. 2017 [citado 20/05/2019]; 8(5): 643-661. Disponible en: http://www.aginganddisease.org/EN/10.14336/AD.2017.0503#1

7. Caccialanza M, et al. Radiotherapy of carcinomas of the skin overlying the cartilage of the nose: our experience in 671 lesions. Journal European Academy of Dermatology and Venereology [Internet]. 2009 [citado 20/05/2021]; 23(9): 1044-1049. Disponible en: https://pubmed.ncbi.nlm.nih.gov/19368616/

8. Butcher LM, et al. Less is more when treating the nasal ala with superficial radiotherapy. International Journal of Radiology & Radiation Therapy [Internet]. 2020 [citado 20/05/2021]; 7(3): 66-69. Disponible en: https://medcraveonline.com/IJRRT/IJRRT-07-00267.pdf

9. Lio Y, et al. Enhancing Cosmesis While Achieving High Cure-Rates For Early-Stage Non-Melanoma Skin Cancer In The Outpatient Dermatology Clinic Using Novel Non-Invasive Modality. American Journal of Biomedical Science and Research [Internet]. 2021 [citado 20/05/2021]; 12(6). Disponible en: https://biomedgrid.com/fulltext/volume12/enhancing-cosmesis-while-achieving-high-cure-rates-for-early-stage-non-melanoma-skin-cancer.001803.php

10. Bertozzi N, Simonacci F, Greco MP, et al. Single center evidence for the treatment of basall cell carcinoma of the head and neck. Acta Biomed [Internet]. 2019 [citado 20/05/2019]; 90(1): 77-82. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30889158/

11. Tighe DG, et al. Definitive radiotherapy for basal cell carcinoma and cutaneous squamous cell carcinoma of the nose. Journal of Dermatology Research [Internet]. 2019 [citado 20/05/2019]; 4(1). Disponible en: http://www.ghrnet.org/index.php/jdr/article/view/2528/2900

12. Cox JD, Stetz J, Pajak TF: Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol BiolPhys [Internet]. 1995 [citado 20/05/2021]; 31(5): 1341-1346. Disponible en: https://pubmed.ncbi.nlm.nih.gov/7713792/

13. Nazco TJ, et al. Tratamiento de tumores de piel con SENSUS SRT-100TM en Centro Oncológico pinareño. Rev Ciencias Médicas [Internet]. 2019 [citado 20/05/2021]; 23(6): 817-826. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=95085

14. Roth W. et al, Long-Term Efficacy and Safety of Superficial Radiation Therapy in Subjects WithNonmelanoma Skin Cancer: A Retrospective Registry Study. J DrugsDermatol [Internet]. 2020[citado 20/05/2021]; 19(2): 163-168. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32129960/

15. Lindelof B. Grenz ray therapy. In: Goldschmidt H, Panizzon RG. Modern dermatologic radiation therapy [Internet]. New York: Springer Verlag; 1991 [citado 20/05/2021]: 155-159. Disponible en: https://link.springer.com/book/10.1007/978-1-4613-9041-1

16. Lovett RD, Perez CA, Shapiro SJ, et al. External Irradiation of epithelial skin cancer Int J Rad Oncol, Biol Physics [Internet]. 1990 [citado 20/05/2021]; 19(2): 235-242. Disponible en: https://pubmed.ncbi.nlm.nih.gov/2394605/

17. Solan MJ, Brady LW, Binnick SA, et al. Skin Cancer. En Pérez CA, Brady LW Eds. Principies and practice of radiation oncology [Internet]. Philadeiphia: JB Lippincott; 1992 [citado 20/05/2021]: 479-495. Disponible en: https://oncology.lwwhealthlibrary.com/Errors/UnauthorizedAccess.aspx

Published

2023-08-06

How to Cite

1.
Martínez-García D, Nazco-Torres J, Castro-Crespo D, Aguiar-Ferro Y, Díaz-Castillo N. Evaluation of cosmetic results of the nasal ala, dorsum and tip of the nose in treatments with SENSUS SRT-100TM. Rev Ciencias Médicas [Internet]. 2023 Aug. 6 [cited 2025 Jul. 31];27:e5898. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/5898