Kawasaki disease and Covid-19: A literature review
Keywords:
COVID-19, RARE DISEASES, SEVERE ACUTE RESPIRATORY SYNDROME, SYSTEMIC VASCULITIS.Abstract
Introduction: Kawasaki disease is considered a rare multisystemic inflammatory disease, generally self-limited. It is considered as an acute systemic vasculitis syndrome affecting mainly small and medium caliber arteries.
Objective: to characterize the relationship between Kawasaki disease and Covid-19.
Methods: a documentary review was carried out through the SciELO, PubMed and Scopus databases. We considered publications in English and Spanish, from March 2022 to March 2023 (12 months), using a total of 16 articles.
Results: COVID-19 is a severe acute respiratory syndrome, however, the respiratory tract does not appear to be the only system susceptible to SARS-CoV-2 infection. COVID-19 infection results in tissue damage and is mediated by innate host immunity, coupled by various factors resulting in the so-called multisystem inflammatory syndrome. Kawasaki disease is shown as a vascular reaction to this infection.
Conclusions: COVID-19 infection can trigger the development of Kawasaki syndrome, due to the systemic inflammatory response; however, it is necessary to correctly differentiate the criteria to make an equivocal diagnosis. Early diagnosis and appropriate treatment contributes to the well-being of the pediatric population in the context of COVID-19 infection.
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