Therapeutic Management of Moderate-Severe Psoriasis Associated with HIV Infection: A Literature Review
Keywords:
PSORIASIS, HIV, PHOTOTHERAPY, RETINOIDS, TREATMENT.Abstract
Introduction: psoriasis is a chronic skin disease that can affect any part of the body and cause itching, pain and discomfort, its severity varies from mild to severe and has a significant impact on the quality of life of those who suffer from it. Psoriasis in individuals with Human Immunodeficiency Virus presents particular challenges, manifesting itself in a more severe and treatment resistant manner.
Objective: to analyze the impact of treatments for psoriasis when HIV is present, identifying current trends in terms of efficacy, safety and possible drug-drug interactions, therapeutic relationship and its clinical implications.
Methods: analysis of original articles and systematic reviews previously carried out that provided information on the therapeutic management of moderate-severe psoriasis associated with HIV infection, in addition, the search for information from different databases such as Scielo, Elsevier, PubMed, Chrocrane, Epistemonikos and different journals including Seimc, Medigraphic Artemis, Recimundo, SCIENCE, MEDICRIT, etc. was prioritized.
Results: the importance of an integral therapeutic approach is emphasized, considering the immunodeficiency associated with the Virus. Treatment will focus on the various measures adopted when treating psoriasis, such as phototherapy, the use of oral retinoids and biological treatment, and we also consider that antiretroviral therapy is fundamental for the treatment of psoriasis.
Conclusions: the review provides a thorough investigation of current therapeutic strategies, highlighting the importance of adapting them to the complexity of HIV coinfection.
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