Behavior of congenital defects in San Luis municipality
Keywords:
Prenatal diagnosis/methods, Infant mortality.Abstract
Introduction: with the advances of obstetric and neonatal care, congenital defects at birth have led to a relative increase in child morbidity and mortality all over the world.Objectives: to assess the incidence of congenital malformations in San Luis municipality during 2000-2009 and to classify them regarding the systems or apparatus affected, to precise the effectiveness of prenatal diagnosis, the decision making of the couple after the diagnosis and repercussion on infant mortality.
Material and method: a retrospective and descriptive study about the congenital defects diagnosed during prenatal periods and after birth at “Epifanio Rojas Gil” polyclinic in San Luis municipality; that was carried out throughout 2000-2009 using the records of prenatal diagnosis in the genetic services, which enriched the analysis of the cases assessed in the clinical genetic office.
Results: the incidence of congenital defects diminished during the second five-year period, showing a much better control and follow-up of women in fertile ages and pregnant women. The majority of the defects were prenatally diagnosed (60%) where ultrasound along with alpha fetoprotein [AFP] analysis were the most effective diagnosis means, mainly during the last five years. Cardiovascular malformations and neural tube defect closure were the most frequent. The rate of infant mortality related to congenital defects was low, however 2003 showed the greatest incidence, prevailing the defects in cardiovascular system, no cases were reported during the last five-year period.
Conclusions: decentralization of genetic services allowed improvements in prevention, early diagnosis and survival of newborn carrying congenital defects in San Luis municipality.
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References
1. Pérez Mateo MT, Fuentes Smith L. Experiencia de Veinte Años del Registro Cubano de Malformaciones Congénitas. Rev Cubana Genet Comunit. [Internet]. 2007 [citado 27 Abr 2012]; 1(2): [aprox. 7 p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v1n2/rcgc01207.pdf
2. Oliva Rodríguez JA, Martínez González LR, Marcheco Teruel B, Arencibia Faire J, García Guevara C, Martínez Rey L. Detección prenatal de defectos congénitos por ultrasonido genético. Manual de normas y procedimientos. Cuba: Centro Nacional de Genética Médica; 2010.
3. Marcheco Teruel B. La genética en la Salud Pública: el desarrollo del acceso de todos a los beneficios. Rev Cubana Genet Comunit [Internet]. 2007 [citado 27 Abr 2012]; 1(1): [Aprox. 4p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v1n1/gcoed107.pdf
4. Marcheco Teruel B. Cuba's Nacional Medical Genetics Program. MEDICC Review [Internet]. 2009 [citado 27 Abr 2012]; 11(1): [Aprox. 3 p.]. Disponible en: http://medicc.org/mediccreview/articles/mr_71.pdf
5. Oliva Rodríguez JA. Ultrasonografía en el 1er. trimestre de la gestación. En: Oliva Rodríguez JA. Ultrasonografía diagnóstica fetal, obstétrica y ginecológica. Ciudad de La Habana: Editorial Ciencias Médicas; 2010. p. 3-18.
6. Menéndez García R. El Valor del ácido fólico en la prevención primaria de defectos congénitos y otras enfermedades del ser humano. Rev Cubana Genet Comunit. [Internet]. 2008 [citado 27 Abr 2012]; 2(1): [Aprox. 8 p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v2n1/rcgc01108.htm
7. Taboada Lugo N, León Mollinedo C, Martínez Chao S, Díaz Inufio O, Quintero Escobar K. Comportamiento de algunos factores de riesgo para malformaciones congénitas mayores en el municipio Ranchuelo. Rev Cubana Obstet Ginecol. [Internet]. 2006 [citado 27 Abr 2012]; 32(2): [Aprox. 13 p.]. Disponible en: http://scielo.sld.cu/pdf/gin/v32n2/gin09206.pdf
8. Menéndez García R, Licourt Otero D, Cabrera Rodríguez N, Sainz Padrón L. El programa de diagnóstico, manejo y prevención de enfermedades genéticas y defectos congénitos en la provincia Pinar del Río: 1998-2007. Rev Cubana Genet Comunit. [Internet]. 2009 [citado 27 Abr 2012]; 3(2-3): [Aprox. 11 p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v3n2_3/pinardelrio.pdf
9. Rojas Betancourt IA. Ética y genética médica en Cuba. Rev Cubana Genet Comunit. [Internet]. 2009 [citado 27 Abr 2012]; 3(1): [Aprox. 2 p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v3n1/pdf/rcgc010109.pdf
10. Rojas Betancourt I, Pérez Mateo MT, La Rosa Lorenzo D, Hernández Hernández N, Chávez Díaz S, Fuentes Smith LE, et al. Comportamiento de los defectos congénitos Mayores en el territorio Sur-Este de la Provincia Habana, 1993-2008. Rev Cubana Genet Comunit. [Internet]. 2010 [Citado 27 Abr 2012]; 4(1): [Aprox. 5 p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v4n1/rgc060110.pdf
11. Taboada Lugo N, Lardoeyt Ferrer R. Primer estudio epidemiológico de los defectos congénitos en Asmara, Eritrea, periodo septiembre 2005-julio 2007. Rev Cubana Genet Comunit. [Internet]. 2008 [citado 27 Abr 2012]; 2(2): [Aprox. 8 p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v2n2/PDFsInfomed/rcgc06208.pdf
12. Santelices Cuervo AM, Llamos Paneque A. Estudio de la incidencia de las muertes fetales y neonatales por malformaciones congénitas en el municipio 10 de Octubre: 1981-2005. Rev Cubana Genet Comunit. [Internet]. 2008 [citado 27 Abr 2012]; 2(3): [Aprox. 5p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v2n3/PDFsInfomed/rcgc08308.pdf
13. Delgado Díaz OL, Lantigua Cruz A, Cruz Martínez G, Díaz Fuentes C, Berdasquera Corcho D, Rodríguez Pérez S. Prevalencia de defectos congénitos en recién nacidos. Rev Cubana Med Gen Integr. [Internet]. 2007 [citado 27 Abr 2012]; 23(3): [Aprox. 8p.]. Disponible en: http://bvs.sld.cu/revistas/mgi/vol23_3_07/mgi07307.htm
14. Vega Valdés A, Vizzuett Martínez R. Frecuencia de malformaciones congénitas en un hospital general de tercer nivel. Rev Mexicana Pediatr. [Internet]. Mar-Abr 2005 [citado 27 Abr 2012]; 72(2): [Aprox. 5p.]. Disponible en: http://www.medigraphic.com/pdfs/pediat/sp-2005/sp052d.pdf
15. Rojas Betancourt IA, González Salvat RM, Padilla Guerra M, Martín Ruiz MR, Lavaut Sánchez K, Fuentes Smith LE. Actitudes de Individuos de La Población Cubana Hacia el Aborto Selectivo. Rev Cubana Genet Comunit. [Internet]. 2007 [citado 27 Abr 2012]; 1(2): [Aprox. 6p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v1n2/rcgc01207.pdf
16. García Guevara C, Arencibia Faife J, Savío Benavides A, García Morejón C, Casanova Arbola R, Preval López A. Evaluación de los resultados del diagnóstico prenatal de cardiopatías congénitas en Cuba durante el año 2006. Rev Cubana Genet Comunit [Internet]. 2008 [citado 27 Abr 2012]; 2(1): [Aprox. 5p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v2n1/rcgc03108.htm
17. García Guevara C, Arencibia Faife J, Hernández Martínez Y, Crespo del Río A, García Morejón C, Savío Benavides A. Valor de la vista ecocardiográfica de los tres vasos en el pesquisaje de cardiopatías congénitas. Rev Cubana Genet Comunit. [Internet]. 2010 [citado 27 Abr 2012]; 4(1): [Aprox. 5p.]. Disponible en: http://bvs.sld.cu/revistas/rcgc/v4n1/rgc020110.pdf

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