Incidence and evolution of cervical epithelial lesions in women under 25 years of age

Authors

  • Raydel Marrero Fernández Universidad de Ciencias Médicas de Pinar del Río,
  • José Guillermo Sanabria Negrín Universidad de Ciencias Médicas de Pinar del Río.
  • Ana Margarita Barrabés Mazón Universidad de Ciencias Médicas de Pinar del Río.
  • Inalvis de la Caridad Cruz Hernández Universidad de Ciencias Médicas de Pinar del Río

Keywords:

ADOLESCENTE, ADULTO JOVEN, NEOPLASIA INTRAEPITELIAL CERVICAL, EVOLUCIÓN CLÍNICA, FACTORES DE RIESGO.

Abstract

Introduction: women under 25 years of age constitute a risk group for uterine cervical lesions and its incidence, temporal trend and the histological evolution of them must be known.

Objective: to evaluate the incidence, trend, risk factors and histological evolution of cervical lesions in women under 25 years of age in Pinar del Río during 12 years (from 2003 to 2014).

Method: analytical study with descriptive components. Population: women of the same age bracket from Pinar del Río. Sample: those with the histopathological diagnosis. Frequencies and rates, Pearson correlation coefficient, X2, Odd Ratio and 95% of Confidence Interval were used for the search of association between the variables.

Results: the number of women with cervical intraepithelial neoplasms increased:  overall rate of 19.3 (2003) vs. 573.0 / 100 000 women (2014). The average annual rate was 200.1 injuries / 100 000 women. An association was found between the age of the first sexual intercourse, the number of sexual partners and the presence of human papilloma virus with the presence of cervical intraepithelial neoplasms (p <0.05). The municipalities with the highest annual incidence were Viñales, Pinar del Río and Sandino; only 4% resolved and 8% evolved to higher degrees of cervical intraepithelial neoplasms after 2 years of follow-up. Invasive cancer was scarce.

Conclusions: cervical intraepithelial neoplasms are the most frequent cervical lesions, and their stability over time corroborates these women should not be included in massive screening programs.

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Author Biographies

Raydel Marrero Fernández, Universidad de Ciencias Médicas de Pinar del Río,

Médico, Especialista de Primer Grado en Histología, Departamento de Ciencias Básicas Biomédicas,

José Guillermo Sanabria Negrín, Universidad de Ciencias Médicas de Pinar del Río.

Médico. Especialista de Segundo Grado en Histología. Profesor Auxiliar y Consultante. Investigador Auxiliar.

Ana Margarita Barrabés Mazón, Universidad de Ciencias Médicas de Pinar del Río.

Médico. Especialista de Primer Grado en Histología. Instructora de Histología.

Inalvis de la Caridad Cruz Hernández, Universidad de Ciencias Médicas de Pinar del Río

Médico. Especialista de Primer Grado en Histología. Instructora de Histología.

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Published

2018-07-05

How to Cite

1.
Marrero Fernández R, Sanabria Negrín JG, Barrabés Mazón AM, Cruz Hernández I de la C. Incidence and evolution of cervical epithelial lesions in women under 25 years of age. Rev Ciencias Médicas [Internet]. 2018 Jul. 5 [cited 2025 Sep. 14];22(4):729-40. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/3600

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Section

ORIGINAL ARTICLES