Brain death and donor maintenance: a three-year experience
Keywords:
BRAIN DEATH, DONATION ORGAN, ETIOLOGY, COMPLICATIONS, TRANSPLANTATION.Abstract
Introduction: encephalic death is a historical reality, which has allowed advances in the field of transplantation; experiences regarding this topic are presented in Pinar del Río.
Objective: to characterize patients with encephalic death and its complications during donor maintenance in the intensive care unit of the General Teaching Hospital of Pinar del Rio from 2014 to 2016.
Methods: a prospective, analytical study was conducted in the intensive care unit of the chosen hospital; the target group was comprised of 150 patients with neurological injury and Glasgow ≤ 8 points, and the sample included 59 patients with brain death.
Results: the coordinator was notified within the first three hours (69,50 %), the diagnosis was completed on the first day (57,63 %), mainly in the intensive care units (69,49 %), the Glasgow scale (6 ± 2,2), full outline of unresponsiveness (4 ± 3,2), and Apache II (26 ± 4,3) determined the mortality, hemorrhagic stroke was the fundamental cause (64,41 %), proven by tomography the deviation of structures of the middle line ≥ 5 mm (84,75 %), the compression of the ventricular system (83,05 %), the erasure of cisterns of the base (74,58 %), and the cerebral hernias (59,32 %) presented (p<0,001), in the diagnosis performed by Doppler the isolated systolic spike predominated (72,88 %), with few familial denies (16,9 %), and increasing the donation to 23,73 pmh.
Conclusions: knowledge and adequate management of encephalic death and its complications increase the life expectancy of the recipient from less organic deterioration.
Downloads
References
1. Machado Curbelo C, Comisión Nacional para la Determinación y Certificación de la Muerte. Resolución para la determinación y certificación de la muerte en Cuba. Rev Neurol [Internet]. 2003 [citado 10/12/2016]; 36(8): [aprox. 7p.]. Disponible en: http://www.sld.cu/galerias/pdf/resolucion-muerte.pdf
2. Piloto Morejón M. Estadística Piloto: paquete estadístico digital educacional para las investigaciones epidemiológicas. Rev de Ciencias Médicas [Internet]. 2010 Oct [citado 12/12/2016]; 14(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942010000400004
3. García Balmaseda A, Miranda Pérez Y, Castillo Viera K. Caracterización clínico imagenológica de la muerte encefálica. Hospital General Docente "Abel Santamaría", 2014-2015. Rev Ciencias Médicas de Pinar del Río [Internet]. 2016 Ene-Feb [citado 10/12/2016]; 20(1): [aprox. 6p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942016000100014
4. Bodía MA, Pont T, Sandiumenge A, Oliver E, Gener J, Badía M, et al. Potencialidad de donación de órganos en muerte encefálica y limitación del tratamiento de soporte vital en los pacientes neurocríticos. Med Intensiva [Internet]. 2015 [citado 06/1/2017]; 39(6): [aprox. 7p.]. Disponible en: http://www.medintensiva.org/es-potencialidad-donacion-organos-muerte-encefalica-articulo-S0210569114002095
5. Díaz Tostadoa S. Importancia y perfil del coordinador de donación en México. Revista de la Facultad de Medicina de la UNAM [Internet]. 2012 Sept-Oct [citado 12/12/2016]; 55(5). Disponible en: http://www.medigraphic.com/pdfs/facmed/un-2012/un125c.pdf
6. Planas Oñate A, González Rivera AE, Sánchez Miranda JM. APACHE II como índice predictor de mortalidad en pacientes neuroquirúrgicos no traumáticos en UCI. Rev Cubana Med Int Emerg [Internet]. 2016 [citado 10/12/2016]; 15(4): [aprox. 11p.]. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/184
7. Pacheco Mena CP. Validación de la escala de four frente a la escala de glasgow para predecir mortalidad en pacientes que se encuentran con alteración del estado de conciencia ingresados en el área de emergencia del Hospital Carlos Andrade Marín en el periodo enero - mayo 2014 [Tesis]. Ecuador: Hospital Carlos Andrade Marín; 2014 [citado 10/12/2016]. Disponible en: http://repositorio.puce.edu.ec/handle/22000/10816
8. Dueñas Jurado JM. Protocolos clínicos de actuación ante el proceso de donación y extracción de órganos y tejidos para trasplante en donación en muerte encefálica. Cuad Med Forense [Internet]. 2015 [citado 10/12/2016]; 21(1-2): [aprox. 6p.]. Disponible en: http://scielo.isciii.es/pdf/cmf/v21n1-2/original4.pdf
9. Escudero D, Valentın MO, Escalante JL, Sanmartın A, Perez Basterrechea M, de Gea J, et al. Intensive care practices in brain death diagnosis and organ donation. Anaesthesia [Internet]. 2015 [citado 10/12/2016]; 70: [aprox. 9p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/26040194
10. Revuelto Rey J, Aldabó Pallás T, Egea Guerrero JJ, Vilches Arenas A, Lara EJ, Gordillo Escobar E. Computed tomography as a tool to detect potential brain dead donors. Med Clin (Barc) [Internet]. 2015 [citado 10/12/2016]; 144(12): [aprox. 5p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25458508
11. Morales Ballesteros O, Pacheco Hoyos N, Antillón Valenzuela JE. Diagnóstico de muerte encefálica, en pacientes con clínica compatible, mediante resonancia magnética cerebral. Anales de Radiología México [Internet]. 2015 [citado 10/12/2016]; 14(3): [aprox. 11p.]. Disponible en: http://new.medigraphic.com/cgi-bin/resumen.cgi?IDARTICULO=60827
12. Planas Oñate A, González Rivera AE, Sánchez Miranda JM, Machado Curbelo C. Doppler transcraneal en el diagnóstico de la muerte encefálica. Rev Cubana Med Int Emerg [Internet]. 2016 [citado 12/12/2016]; 15(3): [aprox. 7p.]. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/168/html_63
13. Querevalú Murillo W, Orozco Guzmán R, Díaz Tostado S. Mantenimiento del donante cadavérico en la Unidad de Terapia Intensiva. Rev Asoc Mex Med Crit y Ter Int [Internet]. 2013 [citado 12/12/2016]; 27(2): [aprox. 7p.]. Disponible en: http://new.medigraphic.com/cgi-bin/resumen.cgi?IDARTICULO=40934
14. Rivera Durón E, Portillo García F, Tenango Soriano V, González Moreno F, Vázquez Salinas C. Negativa familiar en un proceso de donación. Arch Neurocien (Mex) [Internet]. 2014 [citado 10/12/2016]; 19(2): [aprox. 4p.]. Disponible en: http://new.medigraphic.com/cgi-bin/resumen.cgi?IDARTICULO=52415
15. España, Organización Nacional de Trasplantes. Balance de actividad en donación y trasplante en España 2015 [Internet]. España: Ministerio de sanidad, servicios sociales e igualdad; 2016 [citado 10/12/2016]. Disponible en: https://www.msssi.gob.es/gabinete/notasPrensa.do?id=3875

Published
How to Cite
Issue
Section
License
Authors who have publications with this journal agree to the following terms: Authors will retain their copyrights and grant the journal the right of first publication of their work, which will be publication of their work, which will be simultaneously subject to the Creative Commons Attribution License (CC-BY-NC 4.0) that allows third parties to share the work as long as its author and first publication in this journal are indicated.
Authors may adopt other non-exclusive license agreements for distribution of the published version of the work (e.g.: deposit it in an institutional telematic archive or publish it in a volume). Likewise, and according to the recommendations of the Medical Sciences Editorial (ECIMED), authors must declare in each article their contribution according to the CRediT taxonomy (contributor roles). This taxonomy includes 14 roles, which can be used to represent the tasks typically performed by contributors in scientific academic production. It should be consulted in monograph) whenever initial publication in this journal is indicated. Authors are allowed and encouraged to disseminate their work through the Internet (e.g., in institutional telematic archives or on their web page) before and during the submission process, which may produce interesting exchanges and increase citations of the published work. (See The effect of open access). https://casrai.org/credit/