Congenital heart defects in human fetuses with extra cardiac defects

Authors

Keywords:

HEART DEFECTS, CONGENITAL, SKIN ABNORMALITIES, FETUS, HEART.

Abstract

Introduction: cardiac malformations are the most frequent congenital defects in humans. These are structural and functional alterations of the heart, circulatory system and great vessels that develop during cardiac embryogenesis. These defects have an impact on the quality of life of patients and their families, and a better understanding of these defects allows their prevention, diagnosis and treatment.

Objective: to identify the association between congenital heart disease and extracardiac defects in human fetuses.

Methods: an analytical and cross-sectional observational research was carried out in human fetuses obtained from pregnancy terminations performed by indication of Medical Genetics between January 2019 and May 2020 in Pinar del Rio, Cuba. The sample was represented by 42 fetuses, selected through a non-probabilistic purposive sampling. The information was obtained from autopsy reports and requests for termination. Descriptive and inferential statistics were applied to the data obtained.

Results: the study showed that most of the fetuses studied were male; ventricular septal defect was the most frequent cardiovascular defect and that among the extracardiac defects, those with the highest incidence were those of the osteomyoarticular system, showing a significant association with ventricular septal defect.

Conclusions: in human fetuses, osteomyoarticular system defects are associated with specific cardiovascular malformations.

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Author Biography

Isvel Zaldivar Garit, Universidad de Ciencias Médicas de Pinar del Río

Especialista de Primer Grado en Medicina General Integral y Especialista de Primer y Segundo Grado en Embriología Clínica

Presidente del Capítulo provincial de la Sociedad Cubana de Ciencias Básicas Biomédicas

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Published

2022-12-30

How to Cite

1.
Zaldivar Garit I, Guerra Sánchez M, Carbó Ordaz AL, Arteaga Domínguez M, Nuñez Hernández D, Velázquez Hernández Y. Congenital heart defects in human fetuses with extra cardiac defects. Rev Ciencias Médicas [Internet]. 2022 Dec. 30 [cited 2025 Aug. 21];26(6):e5620. Available from: https://revcmpinar.sld.cu/index.php/publicaciones/article/view/5620

Issue

Vol. 26 No. 6 (2022)

Section

ORIGINAL ARTICLES

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